Clinical and Radiologic Characteristics, Surgical Outcomes, and Its Possible Origins of Chondroma of the Dural Convexity
Joint Authors
Li, Chuzhong
Gui, Songbai
Guo, Jing
Fang, Qiuyue
Cao, Lei
Zhang, Yazhuo
Cheng, Jianhua
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-17
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Chondroma of the dural convexity (CDC) is a benign and extremely rare type of intracranial chondroma.
In this study, we reported five CDCs in a single center and reviewed the available literature to determine the clinical characteristics and surgical outcomes and possible origins of the disease.
The clinical data of five patients (4 females) who confirmed to be CDC between 2000 and 2019 in our single center was collected together with 22 cases from literatures.
The clinical characteristics and surgical outcomes were reviewed and analyzed.
Among all the available CDC cases, the mean age was 31±13.7 years; the mean tumor volume was 42.3±40.9 cm3, showing a female predominance (63% vs.
37%).
The tumors showed calcification in 88.2% cases (15/17) on CT scans and hypointense on T1WI (15/19, 78.9%), mixed intense on T2WI (10/18, 55.6%), and inhomogeneous enhancement without dural tail sign after administration of gadolinium (20/21, 95.2%).
Almost all the tumors were misdiagnosed as meningiomas preoperatively.
In addition, almost all image available CDC lesions (24/25, 96%) located across the cranial sutures indicating that the tumor originated from ectopic chondrocytes from adjacent skull sutures.
No tumors recurred after total resection in follow-up.
CDCs are characterized with female predominance and may originate from ectopic chondrocytes from adjacent skull sutures.
The lesion with inhomogeneous contrast enhancement without dural tail sign and avascular in cerebral angiography are key points to be differentiated from meningioma.
The most effective treatment is total resection.
American Psychological Association (APA)
Guo, Jing& Fang, Qiuyue& Cheng, Jianhua& Li, Chuzhong& Gui, Songbai& Zhang, Yazhuo…[et al.]. 2020. Clinical and Radiologic Characteristics, Surgical Outcomes, and Its Possible Origins of Chondroma of the Dural Convexity. BioMed Research International،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1135123
Modern Language Association (MLA)
Guo, Jing…[et al.]. Clinical and Radiologic Characteristics, Surgical Outcomes, and Its Possible Origins of Chondroma of the Dural Convexity. BioMed Research International No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1135123
American Medical Association (AMA)
Guo, Jing& Fang, Qiuyue& Cheng, Jianhua& Li, Chuzhong& Gui, Songbai& Zhang, Yazhuo…[et al.]. Clinical and Radiologic Characteristics, Surgical Outcomes, and Its Possible Origins of Chondroma of the Dural Convexity. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1135123
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135123