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Human Organ-Specific 3D Cancer Models Produced by the Stromal Self-Assembly Method of Tissue Engineering for the Study of Solid Tumors
Joint Authors
Auger, François A.
Bolduc, Stéphane
Germain, Lucie
Roy, Vincent
Magne, Brice
Vaillancourt-Audet, Maude
Blais, Mathieu
Grammond, Emil
Piquet, Léo
Fradette, Julie
Laverdière, Isabelle
Moulin, Véronique J.
Landreville, Solange
Gros-Louis, François
Chabaud, Stéphane
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-23, 23 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-14
Country of Publication
Egypt
No. of Pages
23
Main Subjects
Abstract EN
Cancer research has considerably progressed with the improvement of in vitro study models, helping to understand the key role of the tumor microenvironment in cancer development and progression.
Over the last few years, complex 3D human cell culture systems have gained much popularity over in vivo models, as they accurately mimic the tumor microenvironment and allow high-throughput drug screening.
Of particular interest, in vitrohuman 3D tissue constructs, produced by the self-assembly method of tissue engineering, have been successfully used to model the tumor microenvironment and now represent a very promising approach to further develop diverse cancer models.
In this review, we describe the importance of the tumor microenvironment and present the existing in vitro cancer models generated through the self-assembly method of tissue engineering.
Lastly, we highlight the relevance of this approach to mimic various and complex tumors, including basal cell carcinoma, cutaneous neurofibroma, skin melanoma, bladder cancer, and uveal melanoma.
American Psychological Association (APA)
Roy, Vincent& Magne, Brice& Vaillancourt-Audet, Maude& Blais, Mathieu& Chabaud, Stéphane& Grammond, Emil…[et al.]. 2020. Human Organ-Specific 3D Cancer Models Produced by the Stromal Self-Assembly Method of Tissue Engineering for the Study of Solid Tumors. BioMed Research International،Vol. 2020, no. 2020, pp.1-23.
https://search.emarefa.net/detail/BIM-1135456
Modern Language Association (MLA)
Roy, Vincent…[et al.]. Human Organ-Specific 3D Cancer Models Produced by the Stromal Self-Assembly Method of Tissue Engineering for the Study of Solid Tumors. BioMed Research International No. 2020 (2020), pp.1-23.
https://search.emarefa.net/detail/BIM-1135456
American Medical Association (AMA)
Roy, Vincent& Magne, Brice& Vaillancourt-Audet, Maude& Blais, Mathieu& Chabaud, Stéphane& Grammond, Emil…[et al.]. Human Organ-Specific 3D Cancer Models Produced by the Stromal Self-Assembly Method of Tissue Engineering for the Study of Solid Tumors. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-23.
https://search.emarefa.net/detail/BIM-1135456
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135456