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PiperacillinTazobactam as Cause of Acute Generalized Exanthematous Pustulosis
Joint Authors
Kyriakou, Aikaterini
Galanis, Nikiforos
Zagalioti, Sofia-Chrysovalantou
Lazaridou, Elizabeth
Patsatsi, Aikaterini
Source
Case Reports in Dermatological Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-24
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous adverse reaction mainly attributed to antibiotics.
It is characterized by numerous, nonfollicular, sterile pustules, arising on an exanthematous and edematous base.
It is a serious adverse reaction accompanied by fever and leukocytosis.
Piperacillin/tazobactam is indicated for the treatment of patients with moderate to severe infections.
Herein is reported a case of AGEP caused by piperacillin/tazobactam.
A 78-year-old woman with metastatic breast cancer was presented to the emergency department reporting fever and groin pain.
The laboratory analysis and more specifically urine cultivation showed a urinary tract infection by E.
coli with sensitivity to piperacillin/tazobactam.
She had no known allergies.
She was started on intravenous piperacillin/tazobactam; she improved clinically on the second day, but on the fourth day of intravenous therapy, she developed extensive pustular rash on the folds and anterior proximal thighs, accompanied by fever and neutrophilia.
Piperacillin/tazobactam administration was interrupted and she was given prednisolone for ten days.
The patient improved clinically and her laboratory tests returned to normal after two weeks.
AGEP is an uncommon side effect of piperacillin/tazobactam treatment and there are few cases reported.
American Psychological Association (APA)
Kyriakou, Aikaterini& Zagalioti, Sofia-Chrysovalantou& Patsatsi, Aikaterini& Galanis, Nikiforos& Lazaridou, Elizabeth. 2019. PiperacillinTazobactam as Cause of Acute Generalized Exanthematous Pustulosis. Case Reports in Dermatological Medicine،Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1135583
Modern Language Association (MLA)
Kyriakou, Aikaterini…[et al.]. PiperacillinTazobactam as Cause of Acute Generalized Exanthematous Pustulosis. Case Reports in Dermatological Medicine No. 2019 (2019), pp.1-3.
https://search.emarefa.net/detail/BIM-1135583
American Medical Association (AMA)
Kyriakou, Aikaterini& Zagalioti, Sofia-Chrysovalantou& Patsatsi, Aikaterini& Galanis, Nikiforos& Lazaridou, Elizabeth. PiperacillinTazobactam as Cause of Acute Generalized Exanthematous Pustulosis. Case Reports in Dermatological Medicine. 2019. Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1135583
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135583