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Prognostic Significance of Neutrophil to Lymphocyte Ratio, Lymphocyte to Monocyte Ratio, and Platelet to Lymphocyte Ratio in Patients with Nasopharyngeal Carcinoma
Joint Authors
Tang, Minzhong
Ou, Ningjiang
Lu, Aiying
Li, Jun
Zhong, Weiming
Gao, Jianquan
Zheng, Yuming
Cai, Yonglin
Li, Haifeng
Wu, Huihui
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The peripheral blood neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), and platelet to lymphocyte ratio (PLR) have been reported to correlate with the prognosis of many malignancies.
This study evaluated the prognostic value of pretreatment NLR, LMR, and PLR in nasopharyngeal carcinoma (NPC).
A retrospective analysis of clinical and pathological data of 140 NPC patients without distant metastasis during initial treatment was conducted to identify correlations between NLR, LMR, and PLR and clinicopathological features, overall survival, and progression-free survival.
Cox proportional hazard regression analysis was used to reveal the independent factors affecting the prognosis of NPC patients.
NLR was associated with T staging, N staging, and overall clinical stage grouping of the NPC patients (P<0.05).
NLR ≥ 2.28, LMR < 2.26, and PLR ≥ 174 were significantly associated with a relatively short overall survival (P<0.05).
In addition, NLR ≥ 2.28 was significantly associated with a relatively short progression-free survival (P<0.05).
Cox proportional hazard regression analysis showed that NLR was an independent prognostic factor in NPC.
Pretreatment NLR, LMR, and PLR might be a useful complement to TNM staging in the prognostic assessment of NPC patients.
American Psychological Association (APA)
Lu, Aiying& Li, Haifeng& Zheng, Yuming& Tang, Minzhong& Li, Jun& Wu, Huihui…[et al.]. 2017. Prognostic Significance of Neutrophil to Lymphocyte Ratio, Lymphocyte to Monocyte Ratio, and Platelet to Lymphocyte Ratio in Patients with Nasopharyngeal Carcinoma. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1135656
Modern Language Association (MLA)
Lu, Aiying…[et al.]. Prognostic Significance of Neutrophil to Lymphocyte Ratio, Lymphocyte to Monocyte Ratio, and Platelet to Lymphocyte Ratio in Patients with Nasopharyngeal Carcinoma. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1135656
American Medical Association (AMA)
Lu, Aiying& Li, Haifeng& Zheng, Yuming& Tang, Minzhong& Li, Jun& Wu, Huihui…[et al.]. Prognostic Significance of Neutrophil to Lymphocyte Ratio, Lymphocyte to Monocyte Ratio, and Platelet to Lymphocyte Ratio in Patients with Nasopharyngeal Carcinoma. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1135656
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135656