Prognostic Value of Thyroid Hormone FT3 in General Patients Admitted to the Intensive Care Unit
Joint Authors
Guo, Jianying
Hong, Yanyan
Wang, Zhiyong
Li, Yukun
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Low plasma triiodothyronine (T3) concentration indicates nonthyroidal illness syndrome (NTIS), which might be associated with a poor outcome in patients in the intensive care unit (ICU).
This study evaluated the relationship between NTIS and prognostic indicators in patients admitted to the ICU and examined the fT3 cut-off points that could be associated with 28-day mortality.
This prospective observational study included patients admitted to the ICU of The Third Hospital of Hebei Medical University from February to November 2018.
The baseline variables and the occurrence of low free T3 (FT3) were collected.
The patients were divided into the NTIS (FT3<3.28) and non-NTIS groups.
Among 305 patients, 118 (38.7%) were in the NTIS group.
FT3 (P<0.001) and FT4 (P=0.001) were lower, while the 28-day mortality rate (P<0.001) and hospitalization expenses in ICU (P=0.001) were higher in the NTIS group.
The univariable analyses identified NTIS, FT3, free thyroxine/FT3, APACHEII, sequential organ failure score, duration of mechanical ventilation, creatinine, oxygenation index, white blood cells, albumin, age, and brain natriuretic peptide as being associated with 28-day mortality (all P<0.05).
The cut-off value of FT3 for 28-day mortality was 2.88 pmol/L.
The 28-day mortality rate and hospitalization expenses in the ICU were higher in patients with NTIS.
NTIS was independently associated with 28-day mortality.
American Psychological Association (APA)
Guo, Jianying& Hong, Yanyan& Wang, Zhiyong& Li, Yukun. 2020. Prognostic Value of Thyroid Hormone FT3 in General Patients Admitted to the Intensive Care Unit. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1135738
Modern Language Association (MLA)
Guo, Jianying…[et al.]. Prognostic Value of Thyroid Hormone FT3 in General Patients Admitted to the Intensive Care Unit. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1135738
American Medical Association (AMA)
Guo, Jianying& Hong, Yanyan& Wang, Zhiyong& Li, Yukun. Prognostic Value of Thyroid Hormone FT3 in General Patients Admitted to the Intensive Care Unit. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1135738
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135738