A Unique Case of IGF-2 Induced Hypoglycemia Associated with Hepatocellular Carcinoma
Joint Authors
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-13
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Tumor-induced hypoglycemia (TIH) associated with hepatocellular carcinoma (HCC) results from tumor production of insulin-like growth factor 2 (IGF-2), resulting in recurrent hypoglycemia.
Serum levels of insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), or pro-insulin-like growth factor 2 (pro-IGF-2) are required for the diagnosis.
However, due to the limited availability of testing in many laboratories, this condition is often overlooked.
As this condition is often overlooked, prompt recognition and implementation of tumor directed therapies and/or systemic therapies can help mitigate the consequences of hypoglycemia.
We present a 38-year-old man with advanced multifocal HCC who presented with abdominal pain and was found to have recurrent symptomatic hypoglycemia.
Evaluation revealed elevated levels of IGF-2, suggesting a diagnosis of HCC with production of IGF-2.
American Psychological Association (APA)
Rana, Prachi& Kim, Brian. 2019. A Unique Case of IGF-2 Induced Hypoglycemia Associated with Hepatocellular Carcinoma. Case Reports in Endocrinology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1135739
Modern Language Association (MLA)
Rana, Prachi& Kim, Brian. A Unique Case of IGF-2 Induced Hypoglycemia Associated with Hepatocellular Carcinoma. Case Reports in Endocrinology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1135739
American Medical Association (AMA)
Rana, Prachi& Kim, Brian. A Unique Case of IGF-2 Induced Hypoglycemia Associated with Hepatocellular Carcinoma. Case Reports in Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1135739
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135739