![](/images/graphics-bg.png)
Heterogeneity of Necrotic Changes between Cortical and Cancellous Bone in Mandibular Osteoradionecrosis: A Histopathological Analysis of Resection Margin after Segmental Mandibulectomy
Joint Authors
Akashi, Masaya
Hashikawa, Kazunobu
Wanifuchi, Satoshi
Kusumoto, Junya
Shigeoka, Manabu
Furudoi, Shungo
Terashi, Hiroto
Komori, Takahide
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-30
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background.
This study aimed to analyze differences in necrotic changes between cortical and cancellous bone in resection margins after segmental mandibulectomy for advanced mandibular osteoradionecrosis.
Methods.
Anteroposterior bone specimens from eleven patients who underwent segmental mandibulectomy with simultaneous free fibula flap reconstruction for advanced osteoradionecrosis were analyzed histopathologically for the presence of necrotic bone based on the presence of blood vessels within Haversian canals.
Results.
Ten of eleven (91%) cortices near the inferior border of the mandible at the anterior margins were necrotic.
All cancellous bones at the anterior margins were viable.
Seven of eleven (64%) cortices near the inferior border of the mandible at the posterior margins were necrotic.
Three of eleven (27%) cancellous bones at the posterior margins were necrotic.
Conclusion.
Necrotic changes are more prevalent in cortices than in cancellous bones in mandibular osteoradionecrosis, probably due to a decrease of periosteal blood supply caused by radiotherapy.
American Psychological Association (APA)
Akashi, Masaya& Hashikawa, Kazunobu& Wanifuchi, Satoshi& Kusumoto, Junya& Shigeoka, Manabu& Furudoi, Shungo…[et al.]. 2017. Heterogeneity of Necrotic Changes between Cortical and Cancellous Bone in Mandibular Osteoradionecrosis: A Histopathological Analysis of Resection Margin after Segmental Mandibulectomy. BioMed Research International،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1135758
Modern Language Association (MLA)
Akashi, Masaya…[et al.]. Heterogeneity of Necrotic Changes between Cortical and Cancellous Bone in Mandibular Osteoradionecrosis: A Histopathological Analysis of Resection Margin after Segmental Mandibulectomy. BioMed Research International No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1135758
American Medical Association (AMA)
Akashi, Masaya& Hashikawa, Kazunobu& Wanifuchi, Satoshi& Kusumoto, Junya& Shigeoka, Manabu& Furudoi, Shungo…[et al.]. Heterogeneity of Necrotic Changes between Cortical and Cancellous Bone in Mandibular Osteoradionecrosis: A Histopathological Analysis of Resection Margin after Segmental Mandibulectomy. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1135758
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135758