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Sporadic Medullary Thyroid Carcinoma with Paraneoplastic Cushing Syndrome
Joint Authors
Pivovarova, Aleksandra I.
Patrick, Stephanie
Reddy, Punuru J.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Medullary thyroid cancer (MTC) is a rare form of neoplasm affecting the thyroid gland.
This neuroendocrine tumor is capable of releasing active substances causing systemic manifestation in the form of flushing, diarrhea, and uncommonly, Ectopic Cushing’s syndrome (ECS).
MTC can be hereditary as a part of multiple endocrine neoplasm type 2 syndrome (MEN2) or arise sporadically.
We report a case of a 74-year-old female presenting with chronic diarrhea, in whom diagnosis of sporadic MTC was delayed due to previous history of gastrointestinal (GI) disturbances.
The patient developed liver metastases yielding ACTH dependent Cushing’s Syndrome leading to abnormal clinical presentation and laboratory values driven by elevated cortisol level.
Metastatic MTC should be considered in patients presenting with chronic diarrhea and weakness unexplained by other GI related causes.
American Psychological Association (APA)
Pivovarova, Aleksandra I.& Patrick, Stephanie& Reddy, Punuru J.. 2019. Sporadic Medullary Thyroid Carcinoma with Paraneoplastic Cushing Syndrome. Case Reports in Endocrinology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1135785
Modern Language Association (MLA)
Pivovarova, Aleksandra I.…[et al.]. Sporadic Medullary Thyroid Carcinoma with Paraneoplastic Cushing Syndrome. Case Reports in Endocrinology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1135785
American Medical Association (AMA)
Pivovarova, Aleksandra I.& Patrick, Stephanie& Reddy, Punuru J.. Sporadic Medullary Thyroid Carcinoma with Paraneoplastic Cushing Syndrome. Case Reports in Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1135785
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135785