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Impact of Acute Pancreatic Injury on Sphingolipid Metabolism in the Salivary Glands
Joint Authors
Łukaszuk, Bartłomiej
Ziembicka, Dominika M.
Kurek, Krzysztof
Żendzian-Piotrowska, Małgorzata
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Acute pancreatic injury can be related to both parenchymal (responsible for exocrine functions) and islet (mainly β-cells, responsible for endocrine functions) damage.
During embryonic development, both the salivary glands and the pancreas originate from the foregut, which explains many of the observed histological and functional similarities between these two organs.
The relationship between several diseases of the pancreas and salivary glands, resulting from morphological and functional similarities, is well established.
Sphingolipids constitute a class of biologically active molecules involved in numerous physiological and pathological processes, including acute pancreatitis (AP) and diabetes mellitus.
However, the effect of AP on sphingolipid metabolism in the salivary glands remains uncertain.
In the presented study, we examined the effect of AP and type 1 diabetes mellitus on sphingolipid metabolism in the salivary glands of rats.
We demonstrated that acute pancreatic injury, related to both exocrine and endocrine functions, affects the metabolism of sphingolipids in the parotid, but not submandibular, salivary glands.
American Psychological Association (APA)
Żendzian-Piotrowska, Małgorzata& Ziembicka, Dominika M.& Łukaszuk, Bartłomiej& Kurek, Krzysztof. 2020. Impact of Acute Pancreatic Injury on Sphingolipid Metabolism in the Salivary Glands. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1135830
Modern Language Association (MLA)
Żendzian-Piotrowska, Małgorzata…[et al.]. Impact of Acute Pancreatic Injury on Sphingolipid Metabolism in the Salivary Glands. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1135830
American Medical Association (AMA)
Żendzian-Piotrowska, Małgorzata& Ziembicka, Dominika M.& Łukaszuk, Bartłomiej& Kurek, Krzysztof. Impact of Acute Pancreatic Injury on Sphingolipid Metabolism in the Salivary Glands. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1135830
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135830