Dramatic Response to First Line Single Agent Pembrolizumab in Anaplastic Thyroid Carcinoma
Joint Authors
Spalart, Valérie
Legius, Barbara
Segers, Kurt
Coolen, Johan
Maes, Brigitte
Decoster, Lynn
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-26
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Anaplastic thyroid carcinoma (ATC) is a deadly disease with very limited therapeutic options.
There is an urgent need for new and efficacious drugs.
Unfortunately accrual in clinical trials is problematic because of the rarity of the disease and often poor performance status at diagnosis.
Recently some data have emerged suggesting a role for immunotherapy in the treatment of ATC.
We describe the case of a 75-year-old patient with poor performance status and compromised airway and oesophagus at diagnosis, showing a rapid and dramatic response to first line single agent pembrolizumab.
Disease progression in the brain occurred 16 months after initial diagnosis.
At that time there was ongoing extracranial disease control.
American Psychological Association (APA)
Spalart, Valérie& Legius, Barbara& Segers, Kurt& Coolen, Johan& Maes, Brigitte& Decoster, Lynn. 2019. Dramatic Response to First Line Single Agent Pembrolizumab in Anaplastic Thyroid Carcinoma. Case Reports in Endocrinology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1135855
Modern Language Association (MLA)
Spalart, Valérie…[et al.]. Dramatic Response to First Line Single Agent Pembrolizumab in Anaplastic Thyroid Carcinoma. Case Reports in Endocrinology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1135855
American Medical Association (AMA)
Spalart, Valérie& Legius, Barbara& Segers, Kurt& Coolen, Johan& Maes, Brigitte& Decoster, Lynn. Dramatic Response to First Line Single Agent Pembrolizumab in Anaplastic Thyroid Carcinoma. Case Reports in Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1135855
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135855