Cardiovascular Autonomic Neuropathy Is an Independent Risk Factor for Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes
Joint Authors
Bi, Yan
Jin, Jiewen
Zhu, Dalong
Gu, Tianwei
Li, Ping
Wang, Weimin
Zhu, Liangying
Niu, Qing
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
This study aimed to evaluate the association between cardiovascular autonomic neuropathy (CAN) and left ventricular diastolic dysfunction (LVDD) in type 2 diabetes patients.
Methods.
315 type 2 diabetes patients from inpatients of Drum Tower Hospital were included and classified into no CAN (NCAN), possible CAN (PCAN), and definite CAN (DCAN) based on cardiovascular autonomic reflex tests.
The left ventricular diastolic function was assessed by tissue Doppler imaging echocardiography.
Results.
The distribution of NCAN, PCAN, and DCAN was 11.4%, 51.1%, and 37.5%, respectively.
The proportion of LVDD increased among the groups of NCAN, PCAN, and DCAN (39.4%, 45.3%, and 68.0%, P=0.001).
Patients with DCAN had higher filling pressure (E/e′ ratio) (10.9±2.7 versus 9.4±2.8, P=0.013) and impaired diastolic performance (e′) (6.8±1.7 versus 8.6±2.4, P=0.004) compared with NCAN.
CAN was found to be an independent risk factor for LVDD from the multivariate regression analysis (OR = 1.628, P=0.009, 95% CI 1.131–2.344).
Conclusions.
Our results indicated that CAN was an independent risk marker for the presence of LVDD in patients with diabetes.
Early diagnosis and treatment of CAN are advocated for preventing LVDD in type 2 diabetes.
American Psychological Association (APA)
Jin, Jiewen& Wang, Weimin& Zhu, Liangying& Gu, Tianwei& Niu, Qing& Li, Ping…[et al.]. 2017. Cardiovascular Autonomic Neuropathy Is an Independent Risk Factor for Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1135898
Modern Language Association (MLA)
Jin, Jiewen…[et al.]. Cardiovascular Autonomic Neuropathy Is an Independent Risk Factor for Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1135898
American Medical Association (AMA)
Jin, Jiewen& Wang, Weimin& Zhu, Liangying& Gu, Tianwei& Niu, Qing& Li, Ping…[et al.]. Cardiovascular Autonomic Neuropathy Is an Independent Risk Factor for Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1135898
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135898