![](/images/graphics-bg.png)
Addressing Challenges to Enhance the Bioactives of Withania somnifera through Organ, Tissue, and Cell Culture Based Approaches
Joint Authors
Kaul, Sunil C.
Wadhwa, Renu
Singh, Pritika
Guleri, Rupam
Angurala, Amrita
Kaur, Kuldeep
Kaur, Kulwinder
Pati, Pratap Kumar
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-16
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Withania somnifera is a highly valued medicinal plant in traditional home medicine and is known for a wide range of bioactivities.
Its commercial cultivation is adversely affected by poor seed viability and germination.
Infestation by various pests and pathogens, survival under unfavourable environmental conditions, narrow genetic base, and meager information regarding biosynthesis of secondary metabolites are some of the other existing challenges in the crop.
Biotechnological interventions through organ, tissue, and cell culture provide promising options for addressing some of these issues.
In vitro propagation facilitates conservation and sustainable utilization of the existing germplasms and broadening the genetic base.
It would also provide means for efficient and rapid mass propagation of elite chemotypes and generating uniform plant material round the year for experimentation and industrial applications.
The potential of in vitro cell/organ cultures for the production of therapeutically valuable compounds and their large-scale production in bioreactors has received significant attention in recent years.
In vitro culture system further provides distinct advantage for studying various cellular and molecular processes leading to secondary metabolite accumulation and their regulation.
Engineering plants through genetic transformation and development of hairy root culture system are powerful strategies for modulation of secondary metabolites.
The present review highlights the developments and sketches current scenario in this field.
American Psychological Association (APA)
Singh, Pritika& Guleri, Rupam& Angurala, Amrita& Kaur, Kuldeep& Kaur, Kulwinder& Kaul, Sunil C.…[et al.]. 2017. Addressing Challenges to Enhance the Bioactives of Withania somnifera through Organ, Tissue, and Cell Culture Based Approaches. BioMed Research International،Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1135914
Modern Language Association (MLA)
Singh, Pritika…[et al.]. Addressing Challenges to Enhance the Bioactives of Withania somnifera through Organ, Tissue, and Cell Culture Based Approaches. BioMed Research International No. 2017 (2017), pp.1-15.
https://search.emarefa.net/detail/BIM-1135914
American Medical Association (AMA)
Singh, Pritika& Guleri, Rupam& Angurala, Amrita& Kaur, Kuldeep& Kaur, Kulwinder& Kaul, Sunil C.…[et al.]. Addressing Challenges to Enhance the Bioactives of Withania somnifera through Organ, Tissue, and Cell Culture Based Approaches. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1135914
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135914