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Bronchoscopic Diagnosis and Treatment of Primary Tracheobronchial Amyloidosis: A Retrospective Analysis from China
Joint Authors
Chen, Qiong
Lu, Xiao-Xiao
He, Bixiu
Wang, Ge
He, Baimei
Wang, Lijing
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To assess the value of bronchoscopy in the diagnosis and treatment of primary tracheobronchial amyloidosis (TBA), in order to reduce misdiagnosis rates and improve prognosis.
Methods.
Clinical data of 107 patients with TBA reported from 1981 to 2015 in China were retrospectively analyzed for clinical features, bronchoscopic manifestations, pathologies, treatments, and outcomes.
Results.
105 of 107 TBA patients were pathologically confirmed by bronchoscopy.
Main bronchoscopic manifestations of TBA were single or multiple nodules and masses within tracheobronchial lumens; local or diffuse luminal stenosis and obstruction; luminal wall thickening and rigidity; rough or uneven inner luminal walls; congestion and edema of mucosa, which was friable and prone to bleeding upon touch; and so forth.
53 patients were treated with bronchoscopic interventions, like Nd-YAG laser, high-frequency electrotome cautery, freezing, resection, clamping, argon plasma coagulation (APC), microwaving, stent implantation, drug spraying, and other treatments.
51 patients improved, 1 patient worsened, and 1 died.
Conclusion.
Bronchoscopic biopsy is the primary means of diagnosing TBA.
A variety of bronchoscopic interventions have good short-term effects on TBA.
Bronchoscopy has important value in the diagnosis, severity assessment, treatment, efficacy evaluation, and prognosis of TBA.
American Psychological Association (APA)
Lu, Xiao-Xiao& He, Bixiu& Wang, Ge& He, Baimei& Wang, Lijing& Chen, Qiong. 2017. Bronchoscopic Diagnosis and Treatment of Primary Tracheobronchial Amyloidosis: A Retrospective Analysis from China. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1135931
Modern Language Association (MLA)
Lu, Xiao-Xiao…[et al.]. Bronchoscopic Diagnosis and Treatment of Primary Tracheobronchial Amyloidosis: A Retrospective Analysis from China. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1135931
American Medical Association (AMA)
Lu, Xiao-Xiao& He, Bixiu& Wang, Ge& He, Baimei& Wang, Lijing& Chen, Qiong. Bronchoscopic Diagnosis and Treatment of Primary Tracheobronchial Amyloidosis: A Retrospective Analysis from China. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1135931
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135931