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Infections Caused by HRSV A ON1 Are Predominant among Hospitalized Infants with Bronchiolitis in São Paulo City
Joint Authors
Vieira, Sandra E.
Thomazelli, Luciano M.
de Paulis, Milena
Ferronato, Angela E.
Oliveira, Daniele B.
Martinez, Marina Baquerizo
Durigon, Edison L.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Human respiratory syncytial virus is the main cause of respiratory infections in infants.
Several HRSV genotypes have been described.
Goals.
To describe the main genotypes that caused infections in São Paulo (2013–2015) and to analyze their clinical/epidemiological features.
Methods.
94 infants (0–6 months) with bronchiolitis were studied.
Clinical/epidemiological information was collected; a search for 16 viruses in nasopharyngeal secretion (PCR-real-time and conventional, sequencing, and phylogenetic analyses) was performed.
Results.
The mean age was 2.4 m; 48% were male.
The mean length of hospital stay was 4.4 d (14% in the Intensive Care Unit).
The positive rate of respiratory virus was 98.9%; 73 cases (77.6%) were HRSV (76,7% HRSVA).
HRSVA formed three clusters: ON1 (n=34), NA1 (n=1), and NA2 (n=4).
All HRSVB were found to cluster in the BA genotype (BA9-n=10; BA10-n=3).
Clinical analyses showed no significant differences between the genotype AON1 and other genotypes.
Conclusion.
This study showed a high rate of HRSV detection in bronchiolitis.
HRSVA ON1, which has recently been described in other countries and has not been identified in previous studies in the southeast region of Brazil, was predominant.
The clinical characteristics of the infants that were infected with AON1 were similar to infants with infections by other genotypes.
American Psychological Association (APA)
Vieira, Sandra E.& Thomazelli, Luciano M.& de Paulis, Milena& Ferronato, Angela E.& Oliveira, Daniele B.& Martinez, Marina Baquerizo…[et al.]. 2017. Infections Caused by HRSV A ON1 Are Predominant among Hospitalized Infants with Bronchiolitis in São Paulo City. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1135976
Modern Language Association (MLA)
Vieira, Sandra E.…[et al.]. Infections Caused by HRSV A ON1 Are Predominant among Hospitalized Infants with Bronchiolitis in São Paulo City. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1135976
American Medical Association (AMA)
Vieira, Sandra E.& Thomazelli, Luciano M.& de Paulis, Milena& Ferronato, Angela E.& Oliveira, Daniele B.& Martinez, Marina Baquerizo…[et al.]. Infections Caused by HRSV A ON1 Are Predominant among Hospitalized Infants with Bronchiolitis in São Paulo City. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1135976
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1135976