Adhesion Ileus after Fecal Microbiota Transplantation in Long-Standing Radiation Colitis

Abstract EN

Fecal microbiota transplantation (FMT) is a novel strategy for the therapy of dysbiosis-associated disorders via modulation of the gut microbiota.

Intestinal dysbiosis is associated not only with digestive disorders, but also with a variety of extra-digestive disorders.

A worldwide increasing number of FMT can be expected in the future as well as an increase in adverse events.

We describe the case of a patient with chronic radiation colitis that developed adhesion ileus 2 days after FMT.

Since these problems never occured before and the short time interval favours a causality, we speculate about FMT-induced alterations in gut motility causing a “trapping” of the small intestine in an adhesion and other mechanisms beyond “pure” coincidence.