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3D High-Frequency Ultrasound Imaging of Cartilage-Bone Interface Compared with Micro-CT
Joint Authors
Zheng, Yongping
Wen, Chun-Yi
Zhou, Guang-Quan
Huang, Yan-Ping
Chan, Choi Han
Yan, Chun Hoi
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-01
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Cartilage-bone interface (CBI) is a complex structure which bears important information in pathophysiology of osteoarthritis (OA).
While high-frequency ultrasound (US) has been widely used for the investigation of articular cartilage, 3D imaging of CBI using US is less commonly reported in this field.
Here, we adopted a 3D high-frequency ultrasound imaging approach specifically for the investigation of CBI in human knee samples.
Fifteen osteochondral disks from the tibial plateau of seven OA patients were prepared in vitro and scanned using both high-frequency US and micro-CT imaging.
The 3D morphology of the tidemark was reconstructed and compared using an image registration approach between the two imaging modalities.
Results showed that the 3D tidemark could be well registered between the two imaging methods with a mean surface discrepancy of 33.2±9.9 μm.
Quantitative surface waviness/roughness parameter analysis showed significant correlations between the two imaging modalities.
An intensity projected en face imaging was proposed to probe characteristic details of the CBI such as its perforations.
This study provided evidence for the 3D high-frequency ultrasound as a nonionizing radiation imaging tool potentially useful to evaluate the change of CBI in basic research of join diseases including OA.
American Psychological Association (APA)
Huang, Yan-Ping& Chan, Choi Han& Zhou, Guang-Quan& Zheng, Yongping& Yan, Chun Hoi& Wen, Chun-Yi. 2020. 3D High-Frequency Ultrasound Imaging of Cartilage-Bone Interface Compared with Micro-CT. BioMed Research International،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1136311
Modern Language Association (MLA)
Huang, Yan-Ping…[et al.]. 3D High-Frequency Ultrasound Imaging of Cartilage-Bone Interface Compared with Micro-CT. BioMed Research International No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1136311
American Medical Association (AMA)
Huang, Yan-Ping& Chan, Choi Han& Zhou, Guang-Quan& Zheng, Yongping& Yan, Chun Hoi& Wen, Chun-Yi. 3D High-Frequency Ultrasound Imaging of Cartilage-Bone Interface Compared with Micro-CT. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1136311
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136311