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Somatostatinoma Presented as Double-Duct Sign
Joint Authors
Hammad, Nour
Vakhariya, Cynthia
Raphael, Michael
Zakaria, Ali H.
Source
Case Reports in Gastrointestinal Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-09
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Somatostatinoma is a rare neuroendocrine tumor with an incidence rate of 1 in 40 million people.
It presents mostly as asymptomatic tumor diagnosed incidentally on imaging or surgery when evaluating or treating possible causes of abdominal pain.
It also can present with vague symptoms, or as a clinical triad of glucose intolerance, steatorrhea, and achlorhydria.
The majority of somatostatinomas are present in the pancreatic head, followed by the duodenum, the pancreatic tail, and rarely the ampulla of Vater.
The prognosis is poor as more than 77% of cases present as advanced disease with local invasion or distant metastasis.
Surgical resection is the main treatment for early stage disease.
Other treatment options include somatostatin analogue, molecular targeted therapy, and cytotoxic chemotherapy.
The scarcity of somatostatinoma cases led to the lack of fully formulated treatment options.
Herein, we present a 43-year old male patient who was referred by his primary care physician to our gastroenterology clinic due to elevated liver function test and double-duct sign on CT scan.
We performed an ERCP, which revealed 2 cm ampullary lesion with upstream obstruction.
Biopsies were taken and histopathology was unrevealing.
He underwent a laparoscopic pancreaticoduodenectomy with histopathology revealed stage IIb somatostatinoma.
Treating physicians should hold a high index of suspicion and maintain a broad differential diagnosis of elevated liver enzymes.
American Psychological Association (APA)
Zakaria, Ali H.& Hammad, Nour& Vakhariya, Cynthia& Raphael, Michael. 2019. Somatostatinoma Presented as Double-Duct Sign. Case Reports in Gastrointestinal Medicine،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1136327
Modern Language Association (MLA)
Zakaria, Ali H.…[et al.]. Somatostatinoma Presented as Double-Duct Sign. Case Reports in Gastrointestinal Medicine No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1136327
American Medical Association (AMA)
Zakaria, Ali H.& Hammad, Nour& Vakhariya, Cynthia& Raphael, Michael. Somatostatinoma Presented as Double-Duct Sign. Case Reports in Gastrointestinal Medicine. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1136327
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136327