Monitoring Leiomyoma Response to Uterine Artery Embolization Using Diffusion and Perfusion Indices from Diffusion-Weighted Imaging
Joint Authors
Zhou, Yan
Qu, Jian-Xun
Cao, Mengqiu
Qian, Lijun
Zhang, Xuebin
Suo, Xinjun
Lu, Qing
Zhao, Huilin
Liu, Jialin
Xu, Jianrong
Suo, Shiteng
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To investigate the potential of diffusion and perfusion indices (ADC and perfusion fraction f) from DWI at 3.0 T in monitoring treatment response to uterine artery embolization (UAE) at 6-month follow-up.
Methods.
Twelve female patients with uterine fibroids who underwent 3.0-T pelvic DWI before and 6 months after UAE were included.
ADC and perfusion fraction f were calculated from DWI.
The Wilcoxon signed-rank test and Spearman rank correlation test were used for statistics.
Results.
Seventeen fibroids were studied.
The median ADCs showed a significant increase from 1.20 × 10−3 mm2/s (range, 0.86–1.66 × 10−3 mm2/s) at baseline to 1.56 × 10−3 mm2/s (range, 1.00–1.86 × 10−3 mm2/s) at 6-month follow-up (P=0.0003).
Conversely, the median perfusion fraction f was significantly decreased after UAE (P=0.0001), with a median pre-UAE value of 14.2% (range, 6.7%–17.6%) and a median post-UAE value of 9.2% (range, 3.2%–14.6%).
Significant correlations were found between fibroid volume reduction rate and percentage changes in ADC and perfusion fraction f at 6-month follow-up relative to baseline, with ρ values of −0.50 (P=0.04) and 0.55 (P=0.02), respectively.
Conclusion.
ADC and perfusion fraction f obtained from DWI at 3.0 T may help to evaluate treatment response to UAE.
American Psychological Association (APA)
Cao, Mengqiu& Qian, Lijun& Zhang, Xuebin& Suo, Xinjun& Lu, Qing& Zhao, Huilin…[et al.]. 2017. Monitoring Leiomyoma Response to Uterine Artery Embolization Using Diffusion and Perfusion Indices from Diffusion-Weighted Imaging. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1136411
Modern Language Association (MLA)
Cao, Mengqiu…[et al.]. Monitoring Leiomyoma Response to Uterine Artery Embolization Using Diffusion and Perfusion Indices from Diffusion-Weighted Imaging. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1136411
American Medical Association (AMA)
Cao, Mengqiu& Qian, Lijun& Zhang, Xuebin& Suo, Xinjun& Lu, Qing& Zhao, Huilin…[et al.]. Monitoring Leiomyoma Response to Uterine Artery Embolization Using Diffusion and Perfusion Indices from Diffusion-Weighted Imaging. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1136411
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136411