Aplastic Anemia and Good Syndrome in a Heavily Treated Stage IV Thymoma Patient: A Case Report and Review of the Literature
Joint Authors
Ranieri, Sofia Chiatamone
Trasarti, Stefania
Arleo, Maria Antonietta
Bizzoni, Luisa
Bonanni, Livia
Di Battista, Valeria
Limongiello, Maria Assunta
Nardacci, Maria Grazia
Gentile, Giuseppe
Foà, Robin
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Thymoma is an uncommon slowly growing neoplasm.
It usually presents with paraneoplastic syndromes including the immunodeficiency syndrome called Good syndrome and hematological disorders.
Pure red cell aplasia is a well-recognized complication of thymoma, and aplastic anemia is very rare in association with GS.
We report a case of GS in a heavily treated patient with stage IV thymoma associated with a pure red cell aplasia and an amegakaryocytic thrombocytopenia that evolved into an AA and provide an up-to-date review of the relevant literature.
This is the first case of the association of GS and AA with the coexistence of a heavily treated stage IV thymoma.
The fatal outcome was not related to the progression of the thymoma, but rather to the severe infectious complications.
The combination of lymphopenia and hypogammaglobulinemia typical of GS, coupled to the neutropenia, caused by bone marrow failure, was the main predisposing factor for the unfavourable outcome.
American Psychological Association (APA)
Ranieri, Sofia Chiatamone& Trasarti, Stefania& Arleo, Maria Antonietta& Bizzoni, Luisa& Bonanni, Livia& Di Battista, Valeria…[et al.]. 2019. Aplastic Anemia and Good Syndrome in a Heavily Treated Stage IV Thymoma Patient: A Case Report and Review of the Literature. Case Reports in Hematology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1136452
Modern Language Association (MLA)
Ranieri, Sofia Chiatamone…[et al.]. Aplastic Anemia and Good Syndrome in a Heavily Treated Stage IV Thymoma Patient: A Case Report and Review of the Literature. Case Reports in Hematology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1136452
American Medical Association (AMA)
Ranieri, Sofia Chiatamone& Trasarti, Stefania& Arleo, Maria Antonietta& Bizzoni, Luisa& Bonanni, Livia& Di Battista, Valeria…[et al.]. Aplastic Anemia and Good Syndrome in a Heavily Treated Stage IV Thymoma Patient: A Case Report and Review of the Literature. Case Reports in Hematology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1136452
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136452