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The Efficacy and Safety of Lenalidomide plus Rituximab in an Orbital Relapse of Diffuse Large B-Cell Lymphoma
Joint Authors
Palmieri, R.
Esposito, F.
Meconi, F.
Rapisarda, V. M.
Anemona, L.
Paterno, G.
Vaccarini, S.
Pupo, L.
Cantonetti, M.
Nasso, Daniela
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-12
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
A 74-year-old male with diffuse large B-cell lymphoma, with an Ann Arbor stage IV-A, was submitted to immune-chemotherapy in 2014, with complete remission of the disease.
Two years later, he presented with a left eye swelling leading to exophthalmos and blurred vision.
A core biopsy was performed and revealed a local relapse of the disease.
He was considered unfit for intensive salvage chemotherapy and was treated with a combination of rituximab and lenalidomide.
After six courses of rituximab plus lenalidomide, the patient showed complete remission and was submitted to maintenance therapy with lenalidomide.
After 24 months since the start of lenalidomide monotherapy, we did not observe any progression.
In this experience, rituximab plus lenalidomide, without radiotherapy, was a safe and effective therapeutic combination in an elderly patient with a localized relapse of DLBCL who was unfit to receive more aggressive therapies.
American Psychological Association (APA)
Palmieri, R.& Esposito, F.& Meconi, F.& Rapisarda, V. M.& Anemona, L.& Paterno, G.…[et al.]. 2019. The Efficacy and Safety of Lenalidomide plus Rituximab in an Orbital Relapse of Diffuse Large B-Cell Lymphoma. Case Reports in Hematology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136483
Modern Language Association (MLA)
Palmieri, R.…[et al.]. The Efficacy and Safety of Lenalidomide plus Rituximab in an Orbital Relapse of Diffuse Large B-Cell Lymphoma. Case Reports in Hematology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1136483
American Medical Association (AMA)
Palmieri, R.& Esposito, F.& Meconi, F.& Rapisarda, V. M.& Anemona, L.& Paterno, G.…[et al.]. The Efficacy and Safety of Lenalidomide plus Rituximab in an Orbital Relapse of Diffuse Large B-Cell Lymphoma. Case Reports in Hematology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136483
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136483