![](/images/graphics-bg.png)
Hairy Cell Leukemia Masquerading as Pancytopenia in Pregnancy
Joint Authors
Flavin, Richard
Bacon, Christopher L.
Shackleton, Louisa
Byrne, Bridgette
Barry, Rupert
Flynn, Catherine M.
Langabeer, Stephen E.
McCarron, Sarah L.
O'Brien, David
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-21
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Thrombocytopenia is one of the most common hematological abnormalities observed during pregnancy, and in rare cases, this may be the first indicator of an underlying hematological malignancy.
Hairy cell leukemia (HCL) is an uncommon B-cell lymphoproliferative disorder of which thrombocytopenia is a recurrent presenting feature.
A case of pancytopenia presenting in pregnancy is described in which the thrombocytopenia persisted postpartum coincidental with a vesicular, pustular rash characterised as Sweet’s syndrome.
Hematological, histological, immunophenotypic, and molecular investigations confirmed the presence of HCL.
The patient was treated with cladribine resulting in resolution of Sweet’s syndrome, hematological remission from HCL, and achievement of a normal platelet count.
This case highlights the need to maintain a wide differential diagnosis for presentations of pancytopenia or thrombocytopenia in pregnancy and the requirement for follow-up investigation of unusual cases with a lack of response to steroids or immunoglobulin.
American Psychological Association (APA)
Shackleton, Louisa& Langabeer, Stephen E.& O'Brien, David& McCarron, Sarah L.& Byrne, Bridgette& Barry, Rupert…[et al.]. 2019. Hairy Cell Leukemia Masquerading as Pancytopenia in Pregnancy. Case Reports in Hematology،Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1136501
Modern Language Association (MLA)
Shackleton, Louisa…[et al.]. Hairy Cell Leukemia Masquerading as Pancytopenia in Pregnancy. Case Reports in Hematology No. 2019 (2019), pp.1-3.
https://search.emarefa.net/detail/BIM-1136501
American Medical Association (AMA)
Shackleton, Louisa& Langabeer, Stephen E.& O'Brien, David& McCarron, Sarah L.& Byrne, Bridgette& Barry, Rupert…[et al.]. Hairy Cell Leukemia Masquerading as Pancytopenia in Pregnancy. Case Reports in Hematology. 2019. Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1136501
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136501