![](/images/graphics-bg.png)
Biological versus Clinical Risk Factors in Acute Myeloid Leukemia: Is There a Winner?
Joint Authors
Turra, Alessandro
Polverelli, Nicola
Morello, E.
Borlenghi, E.
Rambaldi, B.
Zanaglio, C.
Dereli Eke, Elif
Gandolfi, L.
Farina, M.
Cattina, Federica
Cancelli, Valeria
Russo, Domenico
Malagola, Michele
Bernardi, Simona
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-11
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We present a case of a patient with a three-month history of peripheral blood cytopenia without a confirmed diagnosis of myelodysplastic syndrome, who developed a favourable-risk acute myeloid leukemia (AML), according to the European Leukemia Net (ELN) criteria.
The patient achieved a complete remission with incomplete platelet recovery (CRi) after induction.
The patient achieved the morphological CR after the first consolidation and completed the first-line treatment with a syngeneic stem cell transplantation (SCT).
A disease relapse occurred after one year of CR (blast cell count in the bone marrow 15%), and the patient was offered a haplo-SCT, which he refused due to personal reasons.
In this paper, we discuss the interplay between clinical and biological risk factors in non-high-risk AML patients and speculate that some old clinical risk factors (e.g., age of the patient, achievement of CR after induction, and previous history of myelodysplastic syndrome) may still impact on the treatment decision algorithm of some of these patients.
American Psychological Association (APA)
Malagola, Michele& Polverelli, Nicola& Cancelli, Valeria& Morello, E.& Turra, Alessandro& Borlenghi, E.…[et al.]. 2019. Biological versus Clinical Risk Factors in Acute Myeloid Leukemia: Is There a Winner?. Case Reports in Hematology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136538
Modern Language Association (MLA)
Malagola, Michele…[et al.]. Biological versus Clinical Risk Factors in Acute Myeloid Leukemia: Is There a Winner?. Case Reports in Hematology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1136538
American Medical Association (AMA)
Malagola, Michele& Polverelli, Nicola& Cancelli, Valeria& Morello, E.& Turra, Alessandro& Borlenghi, E.…[et al.]. Biological versus Clinical Risk Factors in Acute Myeloid Leukemia: Is There a Winner?. Case Reports in Hematology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136538
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136538