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Acute Myeloid Leukemia in an Infant with t(8;19)(p11.2;q13) Translocation: Case Report and a Review of the Literature
Joint Authors
Eason, Ashley C.
Bunting, Silvia T.
Peterson, Jess F.
Saxe, Debra
Sabnis, Himalee S.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Acute myeloid leukemia (AML) patients with t(8;16)(p11.2;p13) constitute a small subgroup with a distinct genetic and clinical profile.
We present a unique case of a female infant with monocytic AML associated with t(8;19)(p11.2;q13.3), a rarely reported variation of t(8;16)(p11.2;p13).
The patient presented with leukemia cutis and demonstrated erythrophagocytosis in the diagnostic bone marrow.
She responded well to standard AML chemotherapy and is currently in remission.
Here, we highlight her case as the youngest AML patient with t(8;19) described in the literature, discuss the significance and prognostic implications of this genetic variant, and review 8p11.2 fusion proteins in AML.
American Psychological Association (APA)
Eason, Ashley C.& Bunting, Silvia T.& Peterson, Jess F.& Saxe, Debra& Sabnis, Himalee S.. 2019. Acute Myeloid Leukemia in an Infant with t(8;19)(p11.2;q13) Translocation: Case Report and a Review of the Literature. Case Reports in Hematology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136561
Modern Language Association (MLA)
Eason, Ashley C.…[et al.]. Acute Myeloid Leukemia in an Infant with t(8;19)(p11.2;q13) Translocation: Case Report and a Review of the Literature. Case Reports in Hematology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1136561
American Medical Association (AMA)
Eason, Ashley C.& Bunting, Silvia T.& Peterson, Jess F.& Saxe, Debra& Sabnis, Himalee S.. Acute Myeloid Leukemia in an Infant with t(8;19)(p11.2;q13) Translocation: Case Report and a Review of the Literature. Case Reports in Hematology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136561
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136561