Acute Myeloid Leukemia in an Infant with t(8;19)‎(p11.2;q13)‎ Translocation: Case Report and a Review of the Literature

Joint Authors

Eason, Ashley C.
Bunting, Silvia T.
Peterson, Jess F.
Saxe, Debra
Sabnis, Himalee S.

Source

Case Reports in Hematology

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-09-08

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases

Abstract EN

Acute myeloid leukemia (AML) patients with t(8;16)(p11.2;p13) constitute a small subgroup with a distinct genetic and clinical profile.

We present a unique case of a female infant with monocytic AML associated with t(8;19)(p11.2;q13.3), a rarely reported variation of t(8;16)(p11.2;p13).

The patient presented with leukemia cutis and demonstrated erythrophagocytosis in the diagnostic bone marrow.

She responded well to standard AML chemotherapy and is currently in remission.

Here, we highlight her case as the youngest AML patient with t(8;19) described in the literature, discuss the significance and prognostic implications of this genetic variant, and review 8p11.2 fusion proteins in AML.

American Psychological Association (APA)

Eason, Ashley C.& Bunting, Silvia T.& Peterson, Jess F.& Saxe, Debra& Sabnis, Himalee S.. 2019. Acute Myeloid Leukemia in an Infant with t(8;19)(p11.2;q13) Translocation: Case Report and a Review of the Literature. Case Reports in Hematology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136561

Modern Language Association (MLA)

Eason, Ashley C.…[et al.]. Acute Myeloid Leukemia in an Infant with t(8;19)(p11.2;q13) Translocation: Case Report and a Review of the Literature. Case Reports in Hematology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1136561

American Medical Association (AMA)

Eason, Ashley C.& Bunting, Silvia T.& Peterson, Jess F.& Saxe, Debra& Sabnis, Himalee S.. Acute Myeloid Leukemia in an Infant with t(8;19)(p11.2;q13) Translocation: Case Report and a Review of the Literature. Case Reports in Hematology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136561

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1136561