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Danazol: An Effective and Underutilised Treatment Option in Diamond-Blackfan Anaemia
Joint Authors
Chiruka, S.
Chai, Kern Y.
Quijano, Cara J.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-01
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Diamond-Blackfan anaemia (DBA) is a rare congenital red cell aplasia that presents in infancy.
The exact molecular mechanism of ineffective erythropoiesis and red cell aplasia remains unclear, rendering targeted therapy elusive.
The mainstay treatment of DBA is with regular blood transfusion and long-term corticosteroids, both of which have long-term side effects.
We report a case of DBA successfully treated with danazol, a synthetic androgen, and suggest that danazol be considered as a viable option in patients who become refractory to steroids and are considered high risk or unfit for allogeneic stem cell transplantation.
American Psychological Association (APA)
Chai, Kern Y.& Quijano, Cara J.& Chiruka, S.. 2019. Danazol: An Effective and Underutilised Treatment Option in Diamond-Blackfan Anaemia. Case Reports in Hematology،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1136593
Modern Language Association (MLA)
Chai, Kern Y.…[et al.]. Danazol: An Effective and Underutilised Treatment Option in Diamond-Blackfan Anaemia. Case Reports in Hematology No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1136593
American Medical Association (AMA)
Chai, Kern Y.& Quijano, Cara J.& Chiruka, S.. Danazol: An Effective and Underutilised Treatment Option in Diamond-Blackfan Anaemia. Case Reports in Hematology. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1136593
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136593