Tuberculosis Treatment Outcomes and Factors Associated with Each of Them in a Cohort Followed Up between 2010 and 2014
Joint Authors
Cavalcanti Rolla, Valeria
Schmaltz, Carolina A. S.
Cardoso, Mayara A.
Brasil, Pedro Emmanuel A. A. do
Sant’Anna, Flavia M.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Tuberculosis treatment has undergone recent changes in Brazil.
Objective.
To assess whether favorable outcomes on tuberculosis therapy improved in recent years.
Methods.
Retrospective observational study, based on primary data of tuberculosis patients, followed at INI-FIOCRUZ, from January 2012 to December 2014.
Results.
The outcomes observed were as follows: cure (80%), default (14%), treatment failure (5%), and death (1%).
HIV infection without antiretroviral therapy [OR 0.34 (0.15–0.79)], tuberculosis diagnosis based on sputum smear [OR 0.22 (0.07–0.74)], drug use [OR 0.22 (0.11–0.46)], and/or treatment interruption due to adverse reactions [OR 0.23 (0.08–0.67)] decreased the chance of cure.
Predictors of default, that is, use of noninjecting drugs [OR 3.00 (95% CL 1.31–6.88)], treatment interruption due to adverse reactions [OR 6.30 (1.81–21.95)], low schooling [OR 2.59 (2.15–5.82)], higher age [OR 0.44 (0.23–0.82)], and female gender [OR 0.28 (0.11–0.71)], reduced the chance of treatment default.
Tuberculosis diagnosis based on sputum smear [OR 7.77 (1.94–31.09)] and/or arterial hypertension [OR 4.07 (1.25–13.18)] was associated with treatment failure.
Conclusion.
Mortality and default were low considering the prevalence of HIV infection; however cure was not significantly increased.
American Psychological Association (APA)
Cardoso, Mayara A.& Brasil, Pedro Emmanuel A. A. do& Schmaltz, Carolina A. S.& Sant’Anna, Flavia M.& Cavalcanti Rolla, Valeria. 2017. Tuberculosis Treatment Outcomes and Factors Associated with Each of Them in a Cohort Followed Up between 2010 and 2014. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1136624
Modern Language Association (MLA)
Cardoso, Mayara A.…[et al.]. Tuberculosis Treatment Outcomes and Factors Associated with Each of Them in a Cohort Followed Up between 2010 and 2014. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1136624
American Medical Association (AMA)
Cardoso, Mayara A.& Brasil, Pedro Emmanuel A. A. do& Schmaltz, Carolina A. S.& Sant’Anna, Flavia M.& Cavalcanti Rolla, Valeria. Tuberculosis Treatment Outcomes and Factors Associated with Each of Them in a Cohort Followed Up between 2010 and 2014. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1136624
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136624