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Flow Cytometric Test with Eosin-5-Maleimide for a Diagnosis of Hereditary Spherocytosis in a Newborn
Joint Authors
Charoenkwan, Pimlak
Fanhchaksai, Kanda
Manowong, Suphara
Natesirinilkul, Rungrote
Sathitsamitphong, Lalita
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-07
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A term male newborn born to a mother who had hereditary spherocytosis presented with neonatal jaundice at 20 hours of life.
Complete blood count showed hemoglobin 17.1 g/dL, MCV 104.2 fL, MCH 32.9 pg, and MCHC 31.6 g/dL.
The patient had indirect hyperbilirubinemia requiring phototherapy.
The maximum total bilirubin level was 12.15 mg/dL at 20 hours of life.
Peripheral blood smear revealed spherocytes, crenated red cells, and polychromasia.
A flow cytometric test with eosin-5-maleimide- (EMA-) labeled RBC was performed in the patient and parents.
The fluorescence histograms of EMA-labeled RBC from the patient and mother were shifted to the left, and the fluorescence ratio when compared with normal was 0.69 and 0.84, respectively.
The flow cytometric test with EMA is useful in supporting the diagnosis of hereditary spherocytosis during newborn period.
American Psychological Association (APA)
Fanhchaksai, Kanda& Manowong, Suphara& Natesirinilkul, Rungrote& Sathitsamitphong, Lalita& Charoenkwan, Pimlak. 2019. Flow Cytometric Test with Eosin-5-Maleimide for a Diagnosis of Hereditary Spherocytosis in a Newborn. Case Reports in Hematology،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1136639
Modern Language Association (MLA)
Fanhchaksai, Kanda…[et al.]. Flow Cytometric Test with Eosin-5-Maleimide for a Diagnosis of Hereditary Spherocytosis in a Newborn. Case Reports in Hematology No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1136639
American Medical Association (AMA)
Fanhchaksai, Kanda& Manowong, Suphara& Natesirinilkul, Rungrote& Sathitsamitphong, Lalita& Charoenkwan, Pimlak. Flow Cytometric Test with Eosin-5-Maleimide for a Diagnosis of Hereditary Spherocytosis in a Newborn. Case Reports in Hematology. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1136639
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136639