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MicroRNAs and Cardiovascular Disease in Diabetes Mellitus
Joint Authors
Shan, Pengfei
Sun, Xue
Ding, Yue
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Cardiovascular disease (CVD) is the major macrovascular complication of diabetes mellitus.
Recently, although CVD morbidity and mortality have decreased as a result of comprehensive control of CVD risk factors, CVD remains the leading cause of death of patients with diabetes in many countries, indicating the potential underlying pathophysiological mechanisms.
MicroRNAs are a class of noncoding, single-stranded RNA molecules that are involved in β-cell function, insulin secretion, insulin resistance, skeletal muscle, and adipose tissue and which play an important role in glucose homeostasis and the pathogenesis of diabetic complications.
Here, we review recent progress in research on microRNAs in endothelial cell and vascular smooth muscle cell dysfunction, macrophage and platelet activation, lipid metabolism abnormality, and cardiomyocyte repolarization in diabetes mellitus.
We also review the progress of microRNAs as potential biomarkers and therapeutic targets of CVD in patients with diabetes.
American Psychological Association (APA)
Ding, Yue& Sun, Xue& Shan, Pengfei. 2017. MicroRNAs and Cardiovascular Disease in Diabetes Mellitus. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1136702
Modern Language Association (MLA)
Sun, Xue…[et al.]. MicroRNAs and Cardiovascular Disease in Diabetes Mellitus. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1136702
American Medical Association (AMA)
Ding, Yue& Sun, Xue& Shan, Pengfei. MicroRNAs and Cardiovascular Disease in Diabetes Mellitus. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1136702
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136702