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Multiple Myeloma in a Patient with ANKRD26-Related Thrombocytopenia Successfully Treated with Combination Therapy and Autologous Stem Cell Transplant
Joint Authors
Husnain, Muhammad
Wang, Trent
Valdes, Maikel
Hoffman, James
Lekakis, Lazaros
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-02
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Ankyrin repeat domain-containing protein 26- (ANKRD26-) related thrombocytopenia is a rare, autosomal dominant condition caused by ANKRD26 gene mutation.
ANKRD26-related thrombocytopenia is characterized by moderate thrombocytopenia with minimal bleeding, normal platelet size, and dysmegakaryopoiesis on bone marrow evaluation.
ANKRD26 mutation has been previously associated with myeloid malignancies, including acute myeloid leukemia, myelodysplastic syndrome, and chronic myeloid leukemia.
We report the first case of multiple myeloma in a patient with ANKRD26 related thrombocytopenia.
The patient was successfully treated with contemporary combination therapy followed by melphalan-conditioned autologous stem cell transplant for his multiple myeloma despite preexisting thrombocytopenia.
American Psychological Association (APA)
Husnain, Muhammad& Wang, Trent& Valdes, Maikel& Hoffman, James& Lekakis, Lazaros. 2019. Multiple Myeloma in a Patient with ANKRD26-Related Thrombocytopenia Successfully Treated with Combination Therapy and Autologous Stem Cell Transplant. Case Reports in Hematology،Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1136751
Modern Language Association (MLA)
Husnain, Muhammad…[et al.]. Multiple Myeloma in a Patient with ANKRD26-Related Thrombocytopenia Successfully Treated with Combination Therapy and Autologous Stem Cell Transplant. Case Reports in Hematology No. 2019 (2019), pp.1-3.
https://search.emarefa.net/detail/BIM-1136751
American Medical Association (AMA)
Husnain, Muhammad& Wang, Trent& Valdes, Maikel& Hoffman, James& Lekakis, Lazaros. Multiple Myeloma in a Patient with ANKRD26-Related Thrombocytopenia Successfully Treated with Combination Therapy and Autologous Stem Cell Transplant. Case Reports in Hematology. 2019. Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1136751
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136751