Benefit of N-Acetylcysteine in Postoperative Hepatic Dysfunction: Case Report and Review of Literature
Joint Authors
John, Preeti R.
Bauerlein, Deanna K.
Akbar, Hashem N.
Loughry, Nora D.
von Rosenvinge, Erik C.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-23
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
N-Acetylcysteine (NAC) is reported to have multiple clinical applications in addition to being the specific antidote for acetaminophen toxicity.
NAC stimulates glutathione biosynthesis, promotes detoxification, and acts directly as a scavenger of free radicals.
It is a powerful antioxidant and a potential treatment option for diseases characterized by the generation of free oxygen radicals.
We present a case of postoperative hepatic dysfunction of multifactorial etiology in a patient with therapeutic acetaminophen levels, where hepatic function improved considerably following administration of intravenous NAC.
This case suggests that NAC should be considered for treatment of acute liver dysfunction in the postoperative setting, even in the absence of elevated acetaminophen levels.
American Psychological Association (APA)
Bauerlein, Deanna K.& Akbar, Hashem N.& von Rosenvinge, Erik C.& Loughry, Nora D.& John, Preeti R.. 2019. Benefit of N-Acetylcysteine in Postoperative Hepatic Dysfunction: Case Report and Review of Literature. Case Reports in Hepatology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136792
Modern Language Association (MLA)
Bauerlein, Deanna K.…[et al.]. Benefit of N-Acetylcysteine in Postoperative Hepatic Dysfunction: Case Report and Review of Literature. Case Reports in Hepatology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1136792
American Medical Association (AMA)
Bauerlein, Deanna K.& Akbar, Hashem N.& von Rosenvinge, Erik C.& Loughry, Nora D.& John, Preeti R.. Benefit of N-Acetylcysteine in Postoperative Hepatic Dysfunction: Case Report and Review of Literature. Case Reports in Hepatology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136792
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136792