Vancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Masquerading as Elusive Sepsis
Joint Authors
Roy, Sumon
Goswamy, Vinay P.
Barssoum, Kirolos N.
Rai, Devesh
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
We present a unique case of vancomycin-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome masquerading as elusive endocarditis.
A 37-year-old female actively using intravenous drugs presented with worsening right upper extremity pain, fever, and chills.
Workup revealed methicillin-resistant staphylococcus aureus (MRSA) bacteremia and multiple right-sided septic pulmonary emboli.
Echocardiogram was negative for vegetation.
Vancomycin was initiated for bacteremia management suspected secondary to right upper extremity abscesses.
However, despite resolution of abscesses, fevers persisted, raising suspicion for endocarditis not detected by echocardiogram.
On hospital day 25, the patient began showing signs of DRESS syndrome, ultimately manifesting as transaminitis, eosinophilia, and a diffuse, maculopapular rash.
Vancomycin was switched to Linezolid and she improved on high dose steroids.
The persistent fevers throughout this hospital course were thought to be an elusive endocarditis before DRESS syndrome fully manifested.
Although Vancomycin-induced DRESS is uncommon, this case highlights the importance of identifying early signs of significant adverse effects.
American Psychological Association (APA)
Roy, Sumon& Goswamy, Vinay P.& Barssoum, Kirolos N.& Rai, Devesh. 2019. Vancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Masquerading as Elusive Sepsis. Case Reports in Immunology،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1136848
Modern Language Association (MLA)
Roy, Sumon…[et al.]. Vancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Masquerading as Elusive Sepsis. Case Reports in Immunology No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1136848
American Medical Association (AMA)
Roy, Sumon& Goswamy, Vinay P.& Barssoum, Kirolos N.& Rai, Devesh. Vancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Masquerading as Elusive Sepsis. Case Reports in Immunology. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1136848
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136848