Sirolimus for the Treatment of Airway Obstruction due to Indolent T-Lymphoblastic Proliferation
Joint Authors
Moughames, Eric
Kiess, Ana P.
Akst, Lee M.
Azar, Antoine
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
Indolent T-lymphoblastic proliferation (iT-LBP) is a rare nonmalignant entity that presents as a proliferation of T-lymphoblasts.
We report a first such case with a recurrent laryngeal obstruction presentation that was successfully controlled with Sirolimus.
Case presentation.
This is the case of a 29-year-old female who presented with a recurrent significant lymphoid hyperplasia in the adenoid and tongue base region as well as a right cervical lymph node.
After repeated adenoidectomies and tonsillectomies, and based on pathological and clinical findings she was diagnosed with iT-LBP.
Trials of radiotherapy and immunotherapy with cyclosporine and rituximab all failed to control the progression of the disease.
Sirolimus was finally able to restrict the growth and improve her symptoms.
Conclusion.
While It-LBP does not usually require treatment, it is important to report cases in which treatment was crucial for the survival of the patient, and the effective role of Sirolimus in doing so, without any major adverse effects.
American Psychological Association (APA)
Moughames, Eric& Kiess, Ana P.& Akst, Lee M.& Azar, Antoine. 2019. Sirolimus for the Treatment of Airway Obstruction due to Indolent T-Lymphoblastic Proliferation. Case Reports in Immunology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136855
Modern Language Association (MLA)
Moughames, Eric…[et al.]. Sirolimus for the Treatment of Airway Obstruction due to Indolent T-Lymphoblastic Proliferation. Case Reports in Immunology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1136855
American Medical Association (AMA)
Moughames, Eric& Kiess, Ana P.& Akst, Lee M.& Azar, Antoine. Sirolimus for the Treatment of Airway Obstruction due to Indolent T-Lymphoblastic Proliferation. Case Reports in Immunology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136855
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136855