Cardiovascular Consequences of Repetitive Arousals over the Entire Sleep Duration
Joint Authors
Huang, Rong
Zhong, Xu
Xiao, Yi
Wu, Yanyan
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objectives.
To explore the cardiovascular effects of nightlong repetitive arousals (RA).
Methods.
Twenty healthy subjects participated in two consecutive sleep studies.
The first one was free of intervention and the second study involved repetitive arousals induced by acoustical stimuli.
Blood pressure, heart rate variability (HRV), arterial stiffness index (ASI), and serum markers including nitric oxide (NO), endothelin-1 (ET-1), C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and vascular endothelial growth factor (VEGF) were studied.
Results.
RA led to overnight elevation in diastolic blood pressure (DBP) but not in systolic blood pressure (SBP).
Regarding HRV, overnight increase in low frequency power (LF) and low frequency to high frequency ratio (LHR) and decrease in high frequency power (HF) were evident.
The relative overnight differences in HF and LHR correlated with the amount of rapid-eye movement (REM) sleep.
RA did not cause detectable change in either ASI or serum markers of interest.
Conclusions.
Nightlong RA alters the sympathovagal modulation significantly and this effect seems to be associated with the amount of REM sleep.
Exposure to RA also causes an elevation in postsleep DBP.
Disturbance to autonomic nervous system (ANS) may precede endothelial dysfunction and increased arterial stiffness as cardiovascular consequences of RA.
American Psychological Association (APA)
Wu, Yanyan& Huang, Rong& Zhong, Xu& Xiao, Yi. 2017. Cardiovascular Consequences of Repetitive Arousals over the Entire Sleep Duration. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1136880
Modern Language Association (MLA)
Wu, Yanyan…[et al.]. Cardiovascular Consequences of Repetitive Arousals over the Entire Sleep Duration. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1136880
American Medical Association (AMA)
Wu, Yanyan& Huang, Rong& Zhong, Xu& Xiao, Yi. Cardiovascular Consequences of Repetitive Arousals over the Entire Sleep Duration. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1136880
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136880