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Antibiotic-Related Adverse Drug Reactions at a Tertiary Care Hospital in South Korea
Joint Authors
Ku, Nam Su
Choi, Jun Yong
Kim, June Myung
Jung, In Young
Kim, Jung Ju
Lee, Se Ju
Kim, Jinnam
Seong, Hye
Jeong, Wooyong
Choi, Heun
Jeong, Su Jin
Han, Sang Hoon
Song, Young Goo
Park, Jung Won
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Adverse drug reactions (ADRs) are any unwanted/uncomfortable effects from medication resulting in physical, mental, and functional injuries.
Antibiotics account for up to 40.9% of ADRs and are associated with several serious outcomes.
However, few reports on ADRs have evaluated only antimicrobial agents.
In this study, we investigated antibiotic-related ADRs at a tertiary care hospital in South Korea.
Methods.
This is a retrospective cohort study that evaluated ADRs to antibiotics that were reported at a 2400-bed tertiary care hospital in 2015.
ADRs reported by physicians, pharmacists, and nurses were reviewed.
Clinical information reported ADRs, type of antibiotic, causality assessment, and complications were evaluated.
Results.
1,277 (62.8%) patients were considered antibiotic-related ADRs based on the World Health Organization-Uppsala Monitoring Center criteria (certain, 2.2%; probable, 35.7%; and possible, 62.1%).
Totally, 44 (3.4%) patients experienced serious ADRs.
Penicillin and quinolones were the most common drugs reported to induce ADRs (both 16.0%), followed by third-generation cephalosporins (14.9%).
The most frequently experienced side effects were skin manifestations (45.1%) followed by gastrointestinal disorders (32.6%).
Conclusion.
Penicillin and quinolones are the most common causative antibiotics for ADRs and skin manifestations were the most frequently experienced symptom.
American Psychological Association (APA)
Jung, In Young& Kim, Jung Ju& Lee, Se Ju& Kim, Jinnam& Seong, Hye& Jeong, Wooyong…[et al.]. 2017. Antibiotic-Related Adverse Drug Reactions at a Tertiary Care Hospital in South Korea. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1136965
Modern Language Association (MLA)
Jung, In Young…[et al.]. Antibiotic-Related Adverse Drug Reactions at a Tertiary Care Hospital in South Korea. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1136965
American Medical Association (AMA)
Jung, In Young& Kim, Jung Ju& Lee, Se Ju& Kim, Jinnam& Seong, Hye& Jeong, Wooyong…[et al.]. Antibiotic-Related Adverse Drug Reactions at a Tertiary Care Hospital in South Korea. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1136965
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136965