![](/images/graphics-bg.png)
Selenium Level in Patients with Vitiligo: A Meta-Analysis
Joint Authors
Li, Xin
Dai, Ting
Xiaoying, Sun
Hongjin, Li
Yaqiong, Zhou
Bo, Liang
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
It has been reported that deficiency of selenium can cause autoimmune disease.
This meta-analysis was aimed at evaluating whether there exits an association between selenium level and vitiligo.
Methods.
A comprehensive search was conducted on PubMed, Embase, China National Knowledge Infrastructure (CNKI), Wanfang Med Online, and China VIP databases from the inception to February 12, 2019.
The main outcome was the standardized mean difference (SMD) with 95% confidence interval (CI) in serum selenium level between vitiligo patients and healthy controls.
Results.
A total of 8 studies with 305 vitiligo patients and 6156 healthy controls were included in this meta-analysis.
The results showed that there was no significant difference in selenium level between vitiligo patients and healthy controls (SMD=0.481, 95%CI=−0.642 to 1.604, Z=0.840, P>0.05).
Further subgroup analysis stratified by area revealed that Asian vitiligo patients had decreased selenium level, while that finding was not observed in Caucasian patients (Asian: SMD=−0.303, 95%CI=−0.603 to −0.004, P<0.05; Caucasian: SMD=0.957, 95%CI=−0.752 to 2.665, P>0.05).
Conclusions.
Although overall selenium level was similar between vitiligo patients and health controls, subgroup analysis showed decreased levels of selenium in Asian vitiligo patients.
It may suggest a clinical tailored administration of selenium supplementation in Asian vitiligo patients.
American Psychological Association (APA)
Dai, Ting& Xiaoying, Sun& Li, Xin& Hongjin, Li& Yaqiong, Zhou& Bo, Liang. 2020. Selenium Level in Patients with Vitiligo: A Meta-Analysis. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1136996
Modern Language Association (MLA)
Dai, Ting…[et al.]. Selenium Level in Patients with Vitiligo: A Meta-Analysis. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1136996
American Medical Association (AMA)
Dai, Ting& Xiaoying, Sun& Li, Xin& Hongjin, Li& Yaqiong, Zhou& Bo, Liang. Selenium Level in Patients with Vitiligo: A Meta-Analysis. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1136996
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136996