Can ACE-I Be a Silent Killer While Normal Renal Functions Falsely Secure Us?
Joint Authors
Abdelaal Ahmed Mahmoud, Ahmed
Campbell, Mark
Blajeva, Margarita
Source
Case Reports in Anesthesiology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The current case report represents a warning against serious hyperkalaemia and acidosis induced by ACE-I during surgical stress while normal renal function could deceive the attending anaesthetist.
Arterial gas analysis for follow-up of haemoglobin loss accidentally discovered hyperkalaemia and acidosis.
Glucose-insulin and furosemide successfully corrected hyperkalaemia after 25 minutes and acidosis after 3 hours.
These complications could be explained by a deficient steroid stress response to surgery secondary to suppression by ACE-I.
Event analysis and database search found that ACE-I induced aldosterone deficiency aggravated by surgical stress response with an inadequate increase in aldosterone secretion due to angiotensin II deficiency as a sequel of ACE-I leading to defective secretion of H+ and K+.
Furosemide is recommended to secrete H+ and K+ compensating for aldosterone deficiency in addition to other antihyperkalaemia measures.
Anaesthetising an ACE-I treated patient requires considering ACE-I as a potential cause of hyperkalaemia and acidosis.
American Psychological Association (APA)
Abdelaal Ahmed Mahmoud, Ahmed& Campbell, Mark& Blajeva, Margarita. 2018. Can ACE-I Be a Silent Killer While Normal Renal Functions Falsely Secure Us?. Case Reports in Anesthesiology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1137006
Modern Language Association (MLA)
Abdelaal Ahmed Mahmoud, Ahmed…[et al.]. Can ACE-I Be a Silent Killer While Normal Renal Functions Falsely Secure Us?. Case Reports in Anesthesiology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1137006
American Medical Association (AMA)
Abdelaal Ahmed Mahmoud, Ahmed& Campbell, Mark& Blajeva, Margarita. Can ACE-I Be a Silent Killer While Normal Renal Functions Falsely Secure Us?. Case Reports in Anesthesiology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1137006
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137006