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Follow-Up (Measurement) of Corrected QT Interval in Adult Patients before and after Lung Transplantation
Joint Authors
Bogossian, Harilaos
Hecker, Matthias
Ghofrani, Ardeschir
Gall, Henning
Becker, Nicole
Wiedenroth, Christoph
Arlt, Matthias
Mayer, Konstantin
Padberg, Winfried
Bandorski, Dirk
Hamm, Christian Wilhelm
Seeger, Werner
Höltgen, Reinhard
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-06
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Prolongation of the corrected QT (QTc) interval is well known for many drugs, some of which are an integral part of the therapeutic regimen after lung transplantation (LTX).
Therefore, we investigated the QTc interval after LTX in the present study.
Patients and Methods.
The medical records of patients after LTX were studied for demographic data, indication of LTX, medication, and baseline and follow-up ECGs.
The QT interval was corrected for the patient’s heart rate using the different formulae of Bazett, Fridericia, Hodges, and Framingham.
Results.
Fifty-nine patients were included.
The mean age ± SD was 55.6±7.8 years (median 58 years).
After LTX, QTc intervals showed no (relevant) changes during follow-up, even though all patients were treated with drugs (in combination) known to bear a risk of prolonged QTc interval and cortisone.
The longest QTc intervals were obtained using Bazett’s formula.
Conclusion.
The QTc interval did not increase under immunosuppressive medication after LTX in our cohort of patients.
We speculate that the concurrent use of cortisone may shorten the QT(c) intervals or cancel out drug-induced prolongation of the QTc interval.
American Psychological Association (APA)
Bandorski, Dirk& Höltgen, Reinhard& Becker, Nicole& Padberg, Winfried& Bogossian, Harilaos& Wiedenroth, Christoph…[et al.]. 2017. Follow-Up (Measurement) of Corrected QT Interval in Adult Patients before and after Lung Transplantation. BioMed Research International،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1137085
Modern Language Association (MLA)
Bandorski, Dirk…[et al.]. Follow-Up (Measurement) of Corrected QT Interval in Adult Patients before and after Lung Transplantation. BioMed Research International No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1137085
American Medical Association (AMA)
Bandorski, Dirk& Höltgen, Reinhard& Becker, Nicole& Padberg, Winfried& Bogossian, Harilaos& Wiedenroth, Christoph…[et al.]. Follow-Up (Measurement) of Corrected QT Interval in Adult Patients before and after Lung Transplantation. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1137085
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137085