Ropivacaine Plasma Concentrations after 192-Hour High Dose Epidural Ropivacaine Infusion in a Pediatric Patient without Side Effects

Joint Authors

van de Vossenberg, Glenn
van der Wal, Selina
Müller, Andrea
Tan, Edward
Vissers, Kris

Source

Case Reports in Anesthesiology

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-3, 3 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-07-11

Country of Publication

Egypt

No. of Pages

3

Main Subjects

Medicine

Abstract EN

This case report discusses continuous epidural administration of ropivacaine 0.56 mg kg−1 h −1 for 8 days in a 7-year-old trauma patient to prevent pain, after performing a lower right and upper left leg guillotine amputation.

Venous sampling after 8 days revealed bound and unbound ropivacaine concentrations of 1.1 mg/l and 0.06 mg/l in plasma, respectively.

Arterial sampling for bound and unbound ropivacaine was 1.2 mg/l and 0.05 mg/l in plasma, respectively.

In this case report, long-term high dose epidural infiltration of ropivacaine did not result in severe side effects or complications.

Further studies are needed to explore safety of these concentrations in larger populations of children.

American Psychological Association (APA)

van de Vossenberg, Glenn& van der Wal, Selina& Müller, Andrea& Tan, Edward& Vissers, Kris. 2018. Ropivacaine Plasma Concentrations after 192-Hour High Dose Epidural Ropivacaine Infusion in a Pediatric Patient without Side Effects. Case Reports in Anesthesiology،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1137102

Modern Language Association (MLA)

van de Vossenberg, Glenn…[et al.]. Ropivacaine Plasma Concentrations after 192-Hour High Dose Epidural Ropivacaine Infusion in a Pediatric Patient without Side Effects. Case Reports in Anesthesiology No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1137102

American Medical Association (AMA)

van de Vossenberg, Glenn& van der Wal, Selina& Müller, Andrea& Tan, Edward& Vissers, Kris. Ropivacaine Plasma Concentrations after 192-Hour High Dose Epidural Ropivacaine Infusion in a Pediatric Patient without Side Effects. Case Reports in Anesthesiology. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1137102

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1137102