Ropivacaine Plasma Concentrations after 192-Hour High Dose Epidural Ropivacaine Infusion in a Pediatric Patient without Side Effects
Joint Authors
van de Vossenberg, Glenn
van der Wal, Selina
Müller, Andrea
Tan, Edward
Vissers, Kris
Source
Case Reports in Anesthesiology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-11
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
This case report discusses continuous epidural administration of ropivacaine 0.56 mg kg−1 h −1 for 8 days in a 7-year-old trauma patient to prevent pain, after performing a lower right and upper left leg guillotine amputation.
Venous sampling after 8 days revealed bound and unbound ropivacaine concentrations of 1.1 mg/l and 0.06 mg/l in plasma, respectively.
Arterial sampling for bound and unbound ropivacaine was 1.2 mg/l and 0.05 mg/l in plasma, respectively.
In this case report, long-term high dose epidural infiltration of ropivacaine did not result in severe side effects or complications.
Further studies are needed to explore safety of these concentrations in larger populations of children.
American Psychological Association (APA)
van de Vossenberg, Glenn& van der Wal, Selina& Müller, Andrea& Tan, Edward& Vissers, Kris. 2018. Ropivacaine Plasma Concentrations after 192-Hour High Dose Epidural Ropivacaine Infusion in a Pediatric Patient without Side Effects. Case Reports in Anesthesiology،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1137102
Modern Language Association (MLA)
van de Vossenberg, Glenn…[et al.]. Ropivacaine Plasma Concentrations after 192-Hour High Dose Epidural Ropivacaine Infusion in a Pediatric Patient without Side Effects. Case Reports in Anesthesiology No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1137102
American Medical Association (AMA)
van de Vossenberg, Glenn& van der Wal, Selina& Müller, Andrea& Tan, Edward& Vissers, Kris. Ropivacaine Plasma Concentrations after 192-Hour High Dose Epidural Ropivacaine Infusion in a Pediatric Patient without Side Effects. Case Reports in Anesthesiology. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1137102
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137102