Fatal Balamuthia mandrillaris Encephalitis
Joint Authors
Source
Case Reports in Infectious Diseases
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Balamuthia mandrillaris is a rare cause of granulomatous meningoencephalitis associated with high mortality.
We report a 69-year-old Caucasian female who presented with a 3-day history of worsening confusion and difficulty with speech.
On admission, she was disoriented and had expressive dysphasia.
Motor examination revealed a right arm pronator drift.
Cerebellar examination showed slowing of finger-nose testing on the left.
She was HIV-negative, but the absolute CD4 count was low.
Neuroimaging showed three cavitary, peripherally enhancing brain lesions, involving the right frontal lobe, the left basal ganglia, and the left cerebellar hemisphere.
She underwent right frontal craniotomy with removal of tan, creamy, partially liquefied necrotic material from the brain, consistent with granulomatous amoebic encephalitis on tissue staining.
Immunohistochemical studies and PCR tests confirmed infection with Balamuthia mandrillaris.
She was started on pentamidine, sulfadiazine, azithromycin, fluconazole, flucytosine, and miltefosine.
The postoperative course was complicated by an ischemic stroke, and she died a few weeks later.
American Psychological Association (APA)
Yohannan, Binoy& Feldman, Mark. 2019. Fatal Balamuthia mandrillaris Encephalitis. Case Reports in Infectious Diseases،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1137169
Modern Language Association (MLA)
Yohannan, Binoy& Feldman, Mark. Fatal Balamuthia mandrillaris Encephalitis. Case Reports in Infectious Diseases No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1137169
American Medical Association (AMA)
Yohannan, Binoy& Feldman, Mark. Fatal Balamuthia mandrillaris Encephalitis. Case Reports in Infectious Diseases. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1137169
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137169