Brucella Periprosthetic Joint Infection Involving Bilateral Knees with Negative Synovial Fluid Alpha-Defensin
Joint Authors
Balkhair, Abdullah
Al Maskari, Sultan
Ibrahim, Shadin
Al Busaidi, Ibrahim
Al Amin, Mohammed
Ba Taher, Hashim
Source
Case Reports in Infectious Diseases
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-14
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Periprosthetic joint infection (PJI) due to Brucella is uncommon despite relatively high endemicity of human brucellosis and its osteoarticular predilection.
We report a case of a 57-year-old woman with bacteraemic brucellosis complicated by Brucella periprosthetic infection of both knee joints occurring a decade after bilateral knee arthroplasty and associated with a negative synovial fluid alpha-defensin test.
The patient was successfully treated with anti-Brucella therapy alone and without surgical revision, resulting in clinical and microbiological cure.
We propose that Brucella should be considered as a possible cause of prosthetic joint infection in the appropriate clinical and epidemiological settings.
A negative synovial fluid alpha-defensin (Synovasure AD test) should not be used as a rule-out test for Brucella PJI.
Brucella PJI without radiological loosening may be treated conservatively and solely with antimicrobial therapy.
American Psychological Association (APA)
Balkhair, Abdullah& Al Maskari, Sultan& Ibrahim, Shadin& Al Busaidi, Ibrahim& Al Amin, Mohammed& Ba Taher, Hashim. 2019. Brucella Periprosthetic Joint Infection Involving Bilateral Knees with Negative Synovial Fluid Alpha-Defensin. Case Reports in Infectious Diseases،Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1137177
Modern Language Association (MLA)
Balkhair, Abdullah…[et al.]. Brucella Periprosthetic Joint Infection Involving Bilateral Knees with Negative Synovial Fluid Alpha-Defensin. Case Reports in Infectious Diseases No. 2019 (2019), pp.1-3.
https://search.emarefa.net/detail/BIM-1137177
American Medical Association (AMA)
Balkhair, Abdullah& Al Maskari, Sultan& Ibrahim, Shadin& Al Busaidi, Ibrahim& Al Amin, Mohammed& Ba Taher, Hashim. Brucella Periprosthetic Joint Infection Involving Bilateral Knees with Negative Synovial Fluid Alpha-Defensin. Case Reports in Infectious Diseases. 2019. Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1137177
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137177