Prognostic Role of Left Ventricular Systolic Function Measured by Speckle Tracking Echocardiography in Septic Shock
Joint Authors
Hai, Pham Dang
Binh, Nguyen Thanh
Hien, Nguyen Viet Quang
Hoang, Nguyen Huy
Hoan, Vu Ngoc
Son, Pham Nguyen
Hoa, Le Thi Viet
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Left ventricular (LV) systolic dysfunction is common in septic shock.
Global longitudinal strain (GLS) measured by speckle tracking echocardiography (STE) is a useful marker of intrinsic left ventricular systolic function.
However, the association between left ventricular GLS and outcome in septic patients is not well understood.
We performed this prospective study to investigate the prognostic value of LV systolic function utilizing speckle tracking echocardiography in patients with septic shock.
Methods.
All the patients with septic shock based on sepsis-3 definition admitted to the intensive care unit were prospectively studied with STE within 24 hours after the onset of septic shock.
Baseline clinical and echocardiographic variables were collected.
The primary outcome was in-hospital mortality.
Results.
During a 19-month period, 90 consecutive patients were enrolled in the study.
The in-hospital mortality rate was 43.3%.
Compared with survivors, nonsurvivors exhibited significantly less negative GLS (−13.1±3.3% versus −15.8±2.9%; p<0.001), which reflected worse LV systolic function.
The area under the ROC curves of GLS for the prediction of mortality was 0.76 (95% CI 0.67 to 0.87).
Patients with GLS>−14.1% showed a significantly higher mortality rate (67.7% versus 15.6%; p<0.0001; log‐rank=23.3; p<0.0001).
In the multivariate analysis, GLS (HR, 1.27; 95% CI 1.07 to 1.50, p=0.005) and SOFA scores (HR, 1.27; 95% CI 1.08 to 1.50, p=0.004) were independent predictors of in-hospital mortality.
Conclusions.
Our study indicated that LV systolic function measured by STE might be associated with mortality in patients with septic shock.
American Psychological Association (APA)
Hai, Pham Dang& Binh, Nguyen Thanh& Hien, Nguyen Viet Quang& Hoang, Nguyen Huy& Hoan, Vu Ngoc& Son, Pham Nguyen…[et al.]. 2020. Prognostic Role of Left Ventricular Systolic Function Measured by Speckle Tracking Echocardiography in Septic Shock. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1137240
Modern Language Association (MLA)
Hai, Pham Dang…[et al.]. Prognostic Role of Left Ventricular Systolic Function Measured by Speckle Tracking Echocardiography in Septic Shock. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1137240
American Medical Association (AMA)
Hai, Pham Dang& Binh, Nguyen Thanh& Hien, Nguyen Viet Quang& Hoang, Nguyen Huy& Hoan, Vu Ngoc& Son, Pham Nguyen…[et al.]. Prognostic Role of Left Ventricular Systolic Function Measured by Speckle Tracking Echocardiography in Septic Shock. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1137240
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137240