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A Case of Alveolar Bleeding from Clotting Abnormality by Cefmetazole
Joint Authors
Araki, Makoto
Nakano, Eri
Fukuoka, Tsubasa
Takeuchi, Nao
Seki, Tomoyuki
Tamai, Michihiro
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-21
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Cephalosporins are one of the most commonly used first-line antibiotics.
In this report, we describe the case of a patient who developed alveolar bleeding due to clotting abnormality following the use of cefmetazole, one of cephalosporins containing an N-methylthiotetrazole (NMTT) side chain.
Compared to other antibiotics, cephalosporins with an NMTT side chain cause a higher degree of bleeding events.
The bleeding tendency is caused by the depletion of vitamin K-dependent clotting factors via inhibition of the vitamin K epoxide reductase.
This mechanism of action is the same as warfarin.
Recent years have seen an increase in the number of patients using direct oral anticoagulants that do not require coagulation tests.
As a consequence, there may be an increase in the number of bleeding events due to anticoagulant drugs and such antibiotics coprescription.
Therefore, this case is an instructive lesson.
American Psychological Association (APA)
Nakano, Eri& Fukuoka, Tsubasa& Takeuchi, Nao& Seki, Tomoyuki& Tamai, Michihiro& Araki, Makoto. 2019. A Case of Alveolar Bleeding from Clotting Abnormality by Cefmetazole. Case Reports in Medicine،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1137305
Modern Language Association (MLA)
Nakano, Eri…[et al.]. A Case of Alveolar Bleeding from Clotting Abnormality by Cefmetazole. Case Reports in Medicine No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1137305
American Medical Association (AMA)
Nakano, Eri& Fukuoka, Tsubasa& Takeuchi, Nao& Seki, Tomoyuki& Tamai, Michihiro& Araki, Makoto. A Case of Alveolar Bleeding from Clotting Abnormality by Cefmetazole. Case Reports in Medicine. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1137305
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137305