The Rising Phoenix-Progesterone as the Main Target of the Medical Therapy for Leiomyoma
Joint Authors
Chill, H. H.
Safrai, M.
Reuveni Salzman, A.
Shushan, A.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Leiomyomas, also known as uterine fibroids, are a common benign tumor in women of reproductive age.
These lesions disrupt the function of the uterus causing menorrhagia and pelvic pressure as well as reproductive disorders.
These women pose a true challenge for clinicians in the attempt of choosing the suitable treatment for each patient.
Patient’s age, interest in fertility preservation, and leiomyoma location and size are all factors to be taken into account when deciding upon the preferable therapeutic option.
For the past few decades, surgical treatment was the only reliable long-term treatment available.
A variety of surgical approaches have been developed over the years but these developments have come at the expense of other treatment options.
The classical medical treatment includes gonadotropin-releasing hormone (GnRH) agonists and antagonists.
These agents are well known for their limited clinical effect as well as their broad spectrum of side effects, inspiring a need for new pharmacological treatments.
In recent years, promising results have been reported with the use of selective progesterone receptor modulators (SPRM).
Long-term clinical trials have shown a reduction in bleeding and shrinkage of leiomyoma mass.
These results instill hope for women suffering from symptomatic leiomyomas seeking an effective, long-term medical option for their condition.
American Psychological Association (APA)
Chill, H. H.& Safrai, M.& Reuveni Salzman, A.& Shushan, A.. 2017. The Rising Phoenix-Progesterone as the Main Target of the Medical Therapy for Leiomyoma. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137329
Modern Language Association (MLA)
Chill, H. H.…[et al.]. The Rising Phoenix-Progesterone as the Main Target of the Medical Therapy for Leiomyoma. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1137329
American Medical Association (AMA)
Chill, H. H.& Safrai, M.& Reuveni Salzman, A.& Shushan, A.. The Rising Phoenix-Progesterone as the Main Target of the Medical Therapy for Leiomyoma. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137329
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137329