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Prevalence of Helicobacter pylori vacA Genotypes and cagA Gene in Dental Plaque of Asymptomatic Mexican Children
Joint Authors
de la Garza-Ramos, Myriam Angelica
Urrutia-Baca, Víctor Hugo
Mendoza-Cantú, Alejandra
Urbina-Ríos, Cynthia Sofía
García-Martínez, Martha Elena
Torre-Martínez, Hilda H. H.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-01
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The variability in Helicobacter pylori vacA and cagA genes has been related to the progression of the gastrointestinal disease; also the presence of H.
pylori in the oral cavity has been associated with periodontal disease in adults, but, in children without dyspeptic symptoms, little is known about this.
We evaluated the prevalence of H.
pylori and the presence of vacA/cagA genotypes in the oral cavity of Mexican children without dyspeptic symptoms.
The gingival status was measured, and dental plaque samples (n=100) were taken.
38% of children were positive for H.
pylori 16S rRNA gene by qPCR.
A significant association between H.
pylori oral infection and gingival status was observed (P<0.001).
In 34.6% (9/26) of mild gingivitis cases, s1m2 genotype was found, while s1m1 was typed in 50% (3/6) of moderate gingivitis.
The cagA prevalence among H.
pylori-positive children was 80.8% (21/26), 83.3% (5/6), and 16.7% (1/6) of cases of mild gingivitis, moderate gingivitis, and nongingivitis, respectively (P<0.001).
The s1m1/cagA+ combinational genotype was the most detected in children with gingivitis.
Our results suggest that the prevalence of H.
pylori and detection of vacA/cagA genotypes-associated gastrointestinal disease in the oral cavity could be related to the progression of gingivitis in asymptomatic children.
American Psychological Association (APA)
Mendoza-Cantú, Alejandra& Urrutia-Baca, Víctor Hugo& Urbina-Ríos, Cynthia Sofía& de la Garza-Ramos, Myriam Angelica& García-Martínez, Martha Elena& Torre-Martínez, Hilda H. H.. 2017. Prevalence of Helicobacter pylori vacA Genotypes and cagA Gene in Dental Plaque of Asymptomatic Mexican Children. BioMed Research International،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1137341
Modern Language Association (MLA)
Mendoza-Cantú, Alejandra…[et al.]. Prevalence of Helicobacter pylori vacA Genotypes and cagA Gene in Dental Plaque of Asymptomatic Mexican Children. BioMed Research International No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1137341
American Medical Association (AMA)
Mendoza-Cantú, Alejandra& Urrutia-Baca, Víctor Hugo& Urbina-Ríos, Cynthia Sofía& de la Garza-Ramos, Myriam Angelica& García-Martínez, Martha Elena& Torre-Martínez, Hilda H. H.. Prevalence of Helicobacter pylori vacA Genotypes and cagA Gene in Dental Plaque of Asymptomatic Mexican Children. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1137341
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137341