Human recombinant erythropoietin in the treatment of anemia of patients with chronic renal failure
Joint Authors
al-Badrani, Imad al-Din Ibrahim
Sadi, Najlaa
Mahmud, Isam Hammu
Source
The Medical Journal of Basrah University
Issue
Vol. 27, Issue 1 (30 Jun. 2009), pp.7-10, 4 p.
Publisher
University of Basrah College of Medicine
Publication Date
2009-06-30
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Topics
Abstract EN
Objective : To compare the effect of small doses of recombinant erythropoietin on anemia of patients with chronic kidney disease who need dialysis and those are not on dialysis.
Design : Case-comparative study.
Setting : Nephrology Department in Al-Salaam Teaching Hospital, Mosul.
Methods : Eighty patients having chronic kidney disease (40 patients needed dialysis and 40 patients needed no dialysis) participated in the study.
Epoetin alfa given s.c.
in a dose of 4000 IU, 2 times weekly.
Hemoglobin was measured before drug administration and every 2 weeks and at the end of the trial period (3 months).
Result : A significant increase of hemoglobin level had been obtained after treatment with erythropoietin in both groups.
Comparison between hemoglobin elevation of both groups ( 3.0 g / l for patients without dialysis and 2.9 g / l for patients with dialysis) revealed a non significant difference (P>0.5).
Conclusion : the present study demonstrated that the administration of epoetin alfa, s.c.
in a dose of 4000 IU twice weekly is effective in the elevation of hemoglobin levels in patients with chronic kidney disease.
The effect is comparable in patients who need dialysis and in patients who need no dialysis, also the effect is similar in both sexes.
American Psychological Association (APA)
Mahmud, Isam Hammu& al-Badrani, Imad al-Din Ibrahim& Sadi, Najlaa. 2009. Human recombinant erythropoietin in the treatment of anemia of patients with chronic renal failure. The Medical Journal of Basrah University،Vol. 27, no. 1, pp.7-10.
https://search.emarefa.net/detail/BIM-113740
Modern Language Association (MLA)
Mahmud, Isam Hammu…[et al.]. Human recombinant erythropoietin in the treatment of anemia of patients with chronic renal failure. The Medical Journal of Basrah University Vol. 27, no. 1 (2009), pp.7-10.
https://search.emarefa.net/detail/BIM-113740
American Medical Association (AMA)
Mahmud, Isam Hammu& al-Badrani, Imad al-Din Ibrahim& Sadi, Najlaa. Human recombinant erythropoietin in the treatment of anemia of patients with chronic renal failure. The Medical Journal of Basrah University. 2009. Vol. 27, no. 1, pp.7-10.
https://search.emarefa.net/detail/BIM-113740
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 10
Record ID
BIM-113740