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Cell-Based Models for Development of Antiatherosclerotic Therapies
Joint Authors
Nikiforov, Nikita G.
Zakiev, Emile R.
Orekhov, Alexander N.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The leading cause of death worldwide is cardiovascular disease.
Among the conditions related to the term, the most prominent one is the development of atherosclerotic plaques in the walls of arteries.
The situation gets even worse with the fact that the plaque development may stay asymptomatic for a prolonged period of time.
When it manifests as a cardiovascular disorder, it is already too late: the unfortunate individual is prescribed with a plethora of synthetic drugs, which are of debatable efficacy in the prevention of atherosclerotic lesions and safety.
Cell models could be useful for the purpose of screening substances potentially effective against atherosclerosis progression and effective in reduction of already present plaques.
In this overview, we present studies making use of in vitro and ex vivo models of atherosclerosis development that can prove valuable for clinical applications.
American Psychological Association (APA)
Zakiev, Emile R.& Nikiforov, Nikita G.& Orekhov, Alexander N.. 2017. Cell-Based Models for Development of Antiatherosclerotic Therapies. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137483
Modern Language Association (MLA)
Zakiev, Emile R.…[et al.]. Cell-Based Models for Development of Antiatherosclerotic Therapies. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1137483
American Medical Association (AMA)
Zakiev, Emile R.& Nikiforov, Nikita G.& Orekhov, Alexander N.. Cell-Based Models for Development of Antiatherosclerotic Therapies. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137483
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137483