Mitochondrial-Targeted Molecular Imaging in Cardiac Disease
Joint Authors
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-30
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The present study aimed to discuss the role of mitochondrion in cardiac function and disease.
The mitochondrion plays a fundamental role in cellular processes ranging from metabolism to apoptosis.
The mitochondrial-targeted molecular imaging could potentially illustrate changes in global and regional cardiac dysfunction.
The collective changes that occur in mitochondrial-targeted molecular imaging probes have been widely explored and developed.
As probes currently used in the preclinical setting still have a lot of shortcomings, the development of myocardial metabolic activity, viability, perfusion, and blood flow molecular imaging probes holds great potential for accurately evaluating the myocardial viability and functional reserve.
The advantages of molecular imaging provide a perspective on investigating the mitochondrial function of the myocardium in vivo noninvasively and quantitatively.
The molecular imaging tracers of single-photon emission computed tomography and positron emission tomography could give more detailed information on myocardial metabolism and restoration.
In this study, series mitochondrial-targeted 99mTc-, 123I-, and 18F-labeled tracers displayed broad applications because they could provide a direct link between mitochondrial dysfunction and cardiac disease.
American Psychological Association (APA)
Li, Jin-hui& Lu, Jing& Zhou, You. 2017. Mitochondrial-Targeted Molecular Imaging in Cardiac Disease. BioMed Research International،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1137506
Modern Language Association (MLA)
Li, Jin-hui…[et al.]. Mitochondrial-Targeted Molecular Imaging in Cardiac Disease. BioMed Research International No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1137506
American Medical Association (AMA)
Li, Jin-hui& Lu, Jing& Zhou, You. Mitochondrial-Targeted Molecular Imaging in Cardiac Disease. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1137506
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137506