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High Prevalence of Leptotrichia amnionii, Atopobium vaginae, Sneathia sanguinegens, and Factor 1 Microbes and Association of Spontaneous Abortion among Korean Women
Joint Authors
Seo, Sang-Soo
Oh, Hea Young
Kim, Mi Kyung
Arokiyaraj, Selvaraj
Kwon, Minji
Kong, Ji Sook
Shin, Moon Kyung
Yu, Ye Lee
Lee, Jae Kwan
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-13
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Objective.
The purpose of this study was to (i) determine the cervical microbial composition in different abortion samples and to (ii) investigate the correlation between spontaneous abortion and cervical microbes in Korean women.
Methods.
We collected cervical swabs from women who had never undergone abortion (N=36), had spontaneous abortion (N=23), and had undergone induced abortion (N=88) and subjected those samples to 16S rRNA pyrosequencing.
Further, factor analysis and correlation between cervical microbiota and spontaneous abortion were evaluated by logistic regression analysis.
Results.
In spontaneous abortion women, 16 S rRNA gene sequences showed significant increases in Atopobium vaginae, Megasphaera spp., Gardnerella vaginalis, Leptotrichia amnionii, and Sneathia sanguinegens compared to women in nonabortion group.
In multivariate logistic regression analysis, A.
vaginae (OD = 11.27; 95% = 1.57–81), L.
amnionii (OD = 11.47; 95% = 1.22–107.94), S.
sanguinegens (OD = 6.89; 95% = 1.07–44.33), and factor 1 microbes (OD = 16.4; 95% = 1.88–42.5) were strongly associated with spontaneous abortion.
Conclusions.
This study showed a high prevalence of L.
amnionii, A.
vaginae, S.
sanguinegens, and factor 1 microbes in spontaneous abortion and association with spontaneous abortion in Korean women.
American Psychological Association (APA)
Seo, Sang-Soo& Arokiyaraj, Selvaraj& Kim, Mi Kyung& Oh, Hea Young& Kwon, Minji& Kong, Ji Sook…[et al.]. 2017. High Prevalence of Leptotrichia amnionii, Atopobium vaginae, Sneathia sanguinegens, and Factor 1 Microbes and Association of Spontaneous Abortion among Korean Women. BioMed Research International،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1137627
Modern Language Association (MLA)
Seo, Sang-Soo…[et al.]. High Prevalence of Leptotrichia amnionii, Atopobium vaginae, Sneathia sanguinegens, and Factor 1 Microbes and Association of Spontaneous Abortion among Korean Women. BioMed Research International No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1137627
American Medical Association (AMA)
Seo, Sang-Soo& Arokiyaraj, Selvaraj& Kim, Mi Kyung& Oh, Hea Young& Kwon, Minji& Kong, Ji Sook…[et al.]. High Prevalence of Leptotrichia amnionii, Atopobium vaginae, Sneathia sanguinegens, and Factor 1 Microbes and Association of Spontaneous Abortion among Korean Women. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1137627
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137627