Identification of Clostridium difficile Asymptomatic Carriers in a Tertiary Care Hospital
Joint Authors
Marra, Alexandre R.
dos Santos, Oscar Fernando Pavão
Edmond, Michael B.
Silva, André Luiz de Oliveira
Martino, Marinês Dalla Valle
Mafra, Ana Carolina Cintra Nunes
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
The diagnosis of Clostridium difficile infection (CDI) increases concern that asymptomatic carriers of toxigenic C.
difficile may be diagnosed with CDI.
Methods.
A matched case control study was conducted in inpatients in a tertiary care center.
The first 50 patients with diarrhea and a positive polymerase chain reaction (PCR) test beginning February 1, 2015, were identified as cases.
Control patients were hospitalized patients receiving antibiotics, but with no diarrhea, housed in a room as close as possible to each case during the same admission time.
A convenience sample of healthcare workers who cared for C.
difficile infected patients was also tested.
Results.
We found two positive PCR results for C.
difficile in controls (4.1%).
None of these healthcare workers were positive for C.
difficile by PCR.
There was no difference between groups with respect to overall antibiotic use before the requested PCR for Clostridium difficile (p=0.359).
The majority of cases had a high proportion of gastrointestinal disorders (71.4%) compared with control (8.2%), p<0.001.
Patients with neoplasia had a higher chance of being identified as cases (p=0.041).
Conclusions.
PCR should not be the only diagnostic tool but should be complementary to other methods and to the medical history.
American Psychological Association (APA)
Silva, André Luiz de Oliveira& Marra, Alexandre R.& Martino, Marinês Dalla Valle& Mafra, Ana Carolina Cintra Nunes& Edmond, Michael B.& dos Santos, Oscar Fernando Pavão. 2017. Identification of Clostridium difficile Asymptomatic Carriers in a Tertiary Care Hospital. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1137634
Modern Language Association (MLA)
Silva, André Luiz de Oliveira…[et al.]. Identification of Clostridium difficile Asymptomatic Carriers in a Tertiary Care Hospital. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1137634
American Medical Association (AMA)
Silva, André Luiz de Oliveira& Marra, Alexandre R.& Martino, Marinês Dalla Valle& Mafra, Ana Carolina Cintra Nunes& Edmond, Michael B.& dos Santos, Oscar Fernando Pavão. Identification of Clostridium difficile Asymptomatic Carriers in a Tertiary Care Hospital. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1137634
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137634