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The Impact of Homocysteine, Vitamin B12, and Vitamin D Levels on Functional Outcome after First-Ever Ischaemic Stroke
Joint Authors
Pavlovic, D.
Markišić, Merdin
Pavlović, Aleksandra M.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We explored the relationship between acute ischaemic stroke (IS) early functional outcome and serum levels of homocysteine, vitamin B12, and D in a noninterventional prospective clinical study.
We enrolled 50 patients with first-ever IS and performed laboratory tests and functional assessment at three time points: on admission and three and six months after stroke.
Modified Rankin Scale (mRS), NIHSS scale, and Barthel index (BI) scores were assessed in all participants by trained examiner blinded to laboratory data.
Patients did not receive treatment that might alter laboratory data.
Admission NIHSS correlated with homocysteine levels (r=0.304, p<0.05), B12 level (r=-0.410, p<0.01), and vitamin D levels (r=-0.465, p<0.01).
Functional outcome measures (BI and mRS) did not significantly correlate with homocysteine and vitamin D3 levels at 3 and 6 months.
However, a positive correlation with vitamin B12 levels was detected for BI both at 3 and 6 months and mRS at 6 months.
Higher serum vitamin B12 levels were associated with better functional outcome at follow-up.
American Psychological Association (APA)
Markišić, Merdin& Pavlović, Aleksandra M.& Pavlovic, D.. 2017. The Impact of Homocysteine, Vitamin B12, and Vitamin D Levels on Functional Outcome after First-Ever Ischaemic Stroke. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1137660
Modern Language Association (MLA)
Markišić, Merdin…[et al.]. The Impact of Homocysteine, Vitamin B12, and Vitamin D Levels on Functional Outcome after First-Ever Ischaemic Stroke. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1137660
American Medical Association (AMA)
Markišić, Merdin& Pavlović, Aleksandra M.& Pavlovic, D.. The Impact of Homocysteine, Vitamin B12, and Vitamin D Levels on Functional Outcome after First-Ever Ischaemic Stroke. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1137660
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137660