A Higher Ovarian Response after Stimulation for IVF Is Related to a Higher Number of Euploid Embryos
Joint Authors
Labarta, Elena
Bosch, Ernesto
Alamá, Pilar
Pellicer, Antonio
Mateu, Emilia
Mercader, Amparo
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This study has analysed the relationship between ovarian response and the number of euploid embryos.
This is a post hoc analysis of a subset of data generated during a prospective cohort study previously published.
Forty-six oocyte donors were subjected to ovarian stimulation with 150 IU of rFSH and 75 IU of hp-hMG in a GnRH agonist long protocol.
Preimplantation genetic screening was performed in all viable embryos.
We observed a positive relationship between ovarian response and the number of euploid embryos.
When ovarian response was above the median (≥17 oocytes), the mean number of euploid embryos per donor was 5.0 ± 2.4, while when <17 oocytes were obtained the mean number of euploid embryos was 2.7 ± 1.4 (p=0.000).
Aneuploidy rate did not increase with ovarian response or gonadotropin doses.
Also, the number of euploid embryos was inversely related to the amount of gonadotropins needed per oocyte obtained (ovarian sensitivity index).
These results suggest that the number of euploid embryos available for embryo transfer increases as the number of oocytes obtained does.
Considering the total number of euploid embryos seems more relevant than the aneuploidy rate.
American Psychological Association (APA)
Labarta, Elena& Bosch, Ernesto& Mercader, Amparo& Alamá, Pilar& Mateu, Emilia& Pellicer, Antonio. 2017. A Higher Ovarian Response after Stimulation for IVF Is Related to a Higher Number of Euploid Embryos. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137687
Modern Language Association (MLA)
Labarta, Elena…[et al.]. A Higher Ovarian Response after Stimulation for IVF Is Related to a Higher Number of Euploid Embryos. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1137687
American Medical Association (AMA)
Labarta, Elena& Bosch, Ernesto& Mercader, Amparo& Alamá, Pilar& Mateu, Emilia& Pellicer, Antonio. A Higher Ovarian Response after Stimulation for IVF Is Related to a Higher Number of Euploid Embryos. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137687
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137687